Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Relationship between social support, physical symptoms, and depression in women with breast cancer and pain.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- The influence of telehealth-based cancer rehabilitation interventions on disability: a systematic review.Journal of cancer survivorship : research and practice · 2023Pooled it
- Strategies for Implementing Palliative Care Services for Cancer Patients in Low- and Middle-Income Countries: A Systematic Review.Inquiry : a journal of medical care organization, provision and financingPooled it
- Effect of the Fit2Thrive Intervention on Patient-reported Outcomes in Breast Cancer Survivors: A Randomized Full Factorial Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Trial
- Distinct Symptom Occurrence Subgroups Among Patients With Colorectal Cancer: Differences in Social Determinants of Health and Diet Quality.Research in nursing & health · 2026Article
- Comparison of Emotional Content in Text Responses From Physicians and AI Chatbots to Patient Health Queries: Cross-Sectional Study.Journal of medical Internet research · 2026Article
- Sexual Identity and Birth Cohort Differences in Social Support and Its Link with Well-Being among Sexual Minority Individuals.Archives of sexual behavior · 2026Article
- Impact of social support on cognitive function in patients with breast cancer undergoing chemotherapy: The chain-mediating role of fatigue and depression.Asia-Pacific journal of oncology nursing · 2025Article
- Mental Health Experiences and Challenges Among Individuals with Myasthenia Gravis: Insights from Patient-Centered, Qualitative Analyses.Advances in therapy · 2025Review
- Phantom Breast Syndrome: Clinical Implications for Oncology Nursing.Clinical journal of oncology nursing · 2025Article
- Pain Acceptance in Chronic Postoperative Pain: Concept Analysis.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2025Article
- The role of oxytocin in mediating the relationships between social factors and chemotherapy-associated cognitive decline in female patients with breast cancer.Psychoneuroendocrinology · 2025Article
- Patients' experiences of cognitive behavioural therapy integrated with activity pacing: a qualitative study.BMC cancer · 2025Article
- Pre-Treatment Perceived Social Support Is Associated With Chemotherapy-Induced Peripheral Neuropathy in Patients With Breast Cancer: A Longitudinal Study.Psychiatry investigation · 2025Article
- Detection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering.BMC cancer · 2025Article
- Corneal epithelial dendritic cells associated with ocular pain in dry eye disease.International journal of ophthalmology · 2025Article
- Article
- Relationship between perceived social support and mental health status of the advanced cancer patients receiving palliative care in Bangladesh.Palliative care and social practice · 2024Article
- The Role of Resilience in the Relationship between Sociodemographic, Clinical Characteristics, and Social Support among Breast Cancer Patients in Serbia.Healthcare (Basel, Switzerland) · 2023Article
- Sense of coherence mediates perceived social support and depressive and anxiety symptoms in cervical cancer patients: a cross-sectional study.BMC psychiatry · 2023Article
- The role of social networks in the self-management support for young women recently diagnosed with breast cancer.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
purposeFatigue and pain are common among women with breast cancer, and often related to depressive symptoms. Social support may influence levels of fatigue, pain interference, and depressive symptoms. We tested a theory-based, structural model examining the relationship between social support (i.e., emotional and instrumental) and depressive symptoms via fatigue and pain interference in women with breast cancer.
methodsWomen (N = 327) with stages I-III breast cancer were enrolled in a randomized trial investigating a behavioral pain intervention. Measures of social support, fatigue, pain interference, and depressive symptoms were completed at enrollment. Data were analyzed using structural equation modeling to test direct and indirect pathways relating social support, fatigue, pain interference, and depressive symptoms.
resultsOur model evidenced good fit. Significant direct effects emerged linking higher levels of emotional support with lower levels of fatigue (β = -.30), pain interference (β = -.32), and depressive symptoms (β = -.31). More instrumental support was significantly associated with more depressive symptoms (β = .11), but not fatigue or pain interference. Higher levels of fatigue (β = .30) and pain interference (β = .34) were significantly related to higher levels of depressive symptoms. More emotional support related to less depressive symptoms via lower levels of fatigue (β = -.09) and pain interference (β = -.11).
conclusionWomen reporting higher levels of emotional support endorsed fewer depressive symptoms, and that relationship was driven by lower levels of fatigue and pain interference. Our results highlight novel pathways that healthcare professionals can leverage to optimize social support topics in psychosocial interventions targeting breast cancer symptoms. This model should be replicated using longitudinal data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.