Evidence map›Paper›PMID 33723662›Full record

Trial reportClinical oral investigations2021

Root coverage of multiple gingival recessions treated with coronally advanced flap associated with xenogeneic acellular dermal matrix or connective tissue graft: a 6-month split-mouth controlled and randomized clinical trial.

Renato Maluta, Mabelle Freitas Monteiro, Daiane Cristina Peruzzo, Julio Cesar Joly

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  4. Treatment of multiple adjacent gingival recessions with an acellular dermal matrix or a connective tissue graft: a Meta-analysis.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Renato MalutaImplantology and Periodontology, São Leopoldo Mandic Research Institute, R. Dr. José Rocha Junqueira, 13 - Pte. Preta, Campinas, SP, 13045-755, Brazil.
Mabelle Freitas MonteiroDepartment of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Av. Limeira, 901 - Areião, Piracicaba, SP, 13414-903, Brazil.ORCID http://orcid.org/0000-0001-9333-4349
Daiane Cristina PeruzzoImplantology and Periodontology, São Leopoldo Mandic Research Institute, R. Dr. José Rocha Junqueira, 13 - Pte. Preta, Campinas, SP, 13045-755, Brazil.
Julio Cesar JolyImplantology and Periodontology, São Leopoldo Mandic Research Institute, R. Dr. José Rocha Junqueira, 13 - Pte. Preta, Campinas, SP, 13045-755, Brazil. joly@implanteperio.com.br.
Faculdade São Leopoldo Mandic · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to compare xenogeneic dermal matrix (XDM) to connective tissue graft (CTG) associated with coronally advanced flap (CAF) in treating Miller's class I and II (RT1) multiple gingival recession in a split-mouth randomized clinical trial. MATERIALS AND

methodsFifteen patients with bilateral Miller's class I and II multiple recessions were selected. The patient's side receiving each treatment was randomly allocated to receive XDM or CTG. The clinical parameters were measured at baseline and 6 months of follow-up.

resultsAt 6 months, no significant difference in the root coverage (RC) (95.28 ± 6.89% for CTG and 92.68 ± 7.35% for XDM) and the keratinized tissue (KT) gain (0.91 ± 0.46 mm for CTG and 0.74 ± 0.39 mm for XDM) was observed between groups (p > 0.05). The CTG group presented higher complete root coverage (CRC) than XDM (60% and 33%, respectively) (p = 0.045). Multiple logistic regression indicated that the XDM (p = 0.01) and the XDM and KT interaction (p = 0.02) negatively interfered in the CRC. A 1-mm increase in the baseline KT when using XDM increases almost 6 times the chance of achieving CRC, and XDM reached a similar CRC probability to CTG when the receptor area presented at least 2 mm of KT.

conclusionsBoth treatments were effective for treating multiple gingival recession; similar KT gain, GR reduction, and RC were obtained for CTG and XDM, while CTG promoted higher CRC than XDM. Moreover, the amount of KT at baseline was determinant for CRC when treating multiple gingival recession with XDM. CLINICAL RELEVANCE: XDM produces limited CRC in sites with a reduced amount of KT.

trial registrationBrazilian Clinical Trials Registry (REBEC) number RBR-56NZQ6.

Indexed as

Acellular DermisGingival RecessionConnective TissueGingivaHumansTooth RootTreatment OutcomeConnective tissue graftMultiple gingival recessionRandomized controlled trialsRoot coverageXenogeneic dermal matrix

Identifiers

PMID33723662
OpenAlexW3138554839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.