Evidence map›Paper›PMID 33723418›Full record

ArticleNature immunology2021

Lessons learned: new insights on the role of cytokines in COVID-19.

Maja Buszko, Aleksandra Nita-Lazar, Jung-Hyun Park, Pamela L Schwartzberg, Daniela Verthelyi, Howard A Young, Amy S Rosenberg

Abstract readConference Proceedings
In one paragraph

Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. AnJournal of virology · 2024
    Article
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  17. TLRs: Innate Immune Sentries against SARS-CoV-2 Infection.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maja BuszkoCellular Immunology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA. maja.buszko@nih.gov.ORCID http://orcid.org/0000-0002-8905-2223
Aleksandra Nita-LazarFunctional Cellular Networks Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
Jung-Hyun ParkExperimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-9547-9055
Pamela L SchwartzbergCell Signaling and Immunity Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
Daniela VerthelyiLaboratory of Innate Immunity, Division of Biotechnology Review and Research-III, Office of Biotechnology Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-5450-3071
Howard A YoungLaboratory of Cancer Immunometabolism, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD, USA.ORCID http://orcid.org/0000-0002-3118-5111
Amy S RosenbergLaboratory of Immunology, Division of Biotechnology Review and Research-III, Office of Biotechnology Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.

Funding

Control of Cytokine Gene Expression in LymphoidMyeloid CellsZIABC009283 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI YOUNG, HOWARD · 2009 to 2024
$22.7M
Genetic and Biochemical Approaches to Tyrosine Kinase and Lymphocyte SignalingZIAAI001240 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SCHWARTZBERG, PAMELA · 2019 to 2025
$18.8M
Post-Transcriptional Regulation of Interleukin-7 Receptor ExpressionZIABC011214 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PARK, JUNG-HYUN · 2009 to 2025
$15.9M
COVID-19 biomarker discoveryZIAAI001264 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NITA-LAZAR, ALEKSANDRA · 2020 to 2023
$109k
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomedical ResearchAge FactorsAnimalsAutoimmunityCOVID-19Cytokine Release SyndromeCytokinesHost-Pathogen InteractionsHumansImmune SystemPrognosisRisk FactorsSARS-CoV-2Systemic Inflammatory Response SyndromeCytokines

Identifiers

PMID33723418
PMCPMC9317654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.