Trial reportScientific reports2021
Type 2 diabetes is more predictable in women than men by multiple anthropometric and biochemical measures.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- New insights into sexual dimorphism in cardiometabolic health.Hormones (Athens, Greece) · 2026Review
- Sex differences in the predictive value of insulin resistance surrogate indicators for prediabetes among Chinese adults aged 18-45 years: a multicenter cohort study.Frontiers in endocrinology · 2026Article
- A comparison of anthropometric indicators in predicting the incidence of diabetes and intermediate hyperglycaemia in Finland: a 22-year observational study.BMC public health · 2025Observational
- Insulin resistance and cancer: molecular links and clinical perspectives.Molecular and cellular biochemistry · 2025Review
- Baseline clinical and biochemical profiles of type 2 diabetes patients enrolled in a lifestyle management program in India, a cross-sectional study.Scientific reports · 2025Article
- Transcriptional dynamics in type 2 diabetes progression is linked with circadian, thermogenic, and cellular stress in human adipose tissue.Communications biology · 2025Article
- Do Time-Dependent Repeated Measures of Anthropometric and Body Composition Indices Improve the Prediction of Incident Diabetes in the Cohort Study? Findings from a Community-Based Korean Genome and Epidemiology Study.Diabetes & metabolism journal · 2025Article
- Factors affecting the survival of prediabetic patients: comparison of Cox proportional hazards model and random survival forest method.BMC medical informatics and decision making · 2024Article
- Gender differential in the pattern and severity of perceived symptoms among diabetes patients in India.Diabetology international · 2024Article
- Identifying diabetes risks among Indonesians: A cross-sectional study in a community setting.Belitung nursing journal · 2024Article
- Sex differences in type 2 diabetes: an opportunity for personalized medicine.Biology of sex differences · 2023Article
- Circulating miRNA as potential biomarkers for diabetes mellitus type 2: should we focus on searching for sex differences?Journal of applied genetics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Men and women are sexually dimorphic but whether common anthropometric and biochemical parameters predict type 2 diabetes (T2D) in different ways has not been well studied. Here we recruit 1579 participants in Hainan Province, China, and group them by sex. We compared the prediction power of common parameters of T2D in two sexes by association, regression, and Receiver Operating Characteristic (ROC) analysis. HbA1c is associated with FPG stronger in women than in men and the regression coefficient is higher, consistent with higher prediction power for T2D. Age, waist circumference, BMI, systolic and diastolic blood pressure, triglyceride levels, total cholesterol, LDL, HDL, fasting insulin, and proinsulin levels all predict T2D better in women. Except for diastolic blood pressure, all parameters associate or tend to associate with FPG stronger in women than in men. Except for diastolic blood pressure and fasting proinsulin, all parameters associate or tend to associate with HbA1c stronger in women than in men. Except for fasting proinsulin and HDL, the regression coefficients of all parameters with FPG and HbA1c were higher in women than in men. Together, by the above anthropometric and biochemical measures, T2D is more readily predicted in women than men, suggesting the importance of sex-based subgroup analysis in T2D research.
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