Evidence map›Paper›PMID 33723315›Full record

ArticleScientific reports2021

Impact of age, sex, and joint form on degenerative lesions of the sacroiliac joints on CT in the normal population.

Katharina Ziegeler, Virginie Kreutzinger, Torsten Diekhoff, Robert Roehle, Denis Poddubnyy, Matthias Pumberger, Bernd Hamm, Kay Geert A Hermann

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
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  5. Review
  6. Article
  7. Article
  8. Sacroiliac joint variants are common and gender-specific but do not predict fracture pattern in pelvic ring injuries.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
  9. Article
  10. Factors affecting postoperative pelvic incidence reduction following surgery for adult spinal deformity.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. The sacroiliac joint across ages - what is normal?Therapeutic advances in musculoskeletal disease · 2024
    Review
  15. Article
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  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Katharina Ziegeler *Department of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany. katharina.ziegeler@charite.de.
Virginie Kreutzinger *Department of Radiology, Vivantes Klinikum am Friedrichshain, Berlin, Germany.
Torsten DiekhoffDepartment of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Robert RoehleInstitute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Denis PoddubnyyDivision of Gastroenterology, Infectious Diseases and Rheumatology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Matthias PumbergerCenter for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Bernd HammDepartment of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Kay Geert A HermannDepartment of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEKlinikum im Friedrichshain · DEZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degeneration of the sacroiliac joints (SIJs) is a common finding, while its underlying cause and development remain incompletely understood. The aim of this investigation was to describe the spatial distribution of degenerative SIJ changes across age groups and to investigate for the first time their relationship to anatomical form and sex. For this IRB-approved investigation, demographic data of 818 patients without SIJ disease were retrieved from electronic patient records. High-resolution computed tomography (CT) datasets of all patients were analysed retrospectively for seven predefined age groups (ten-year increments, from < 25 to ≥ 75). A structured scoring system was applied to assess sclerosis, osteophytes, joint space alterations, and anatomical form. Chi-square tests were used to compare frequencies of degenerative lesions, and logistic regression analyses were performed to investigate associations between demographic data, anatomical form, and the presence of structural lesions. Sclerosis and osteophytes were common findings, with an overall prevalence of 45.7% and 46.8%, respectively. Female sex had an odds ratio (OR) of 0.15 (95% CI: 0.08-0.27) for the presence of ventral osteophytes and of 4.42 (95% CI: 2.77-7.04) for dorsal osteophytes. Atypical joint forms were significantly more prevalent in women with 62.1% vs. 14.1% in men (p < 0.001). Accessory joints increased the likelihood of dorsal sclerosis (OR 2.735; 95% CI 1.376-5.436) while a typical joint form decreased its likelihood (OR 0.174; 95% CI 0.104-0.293). Sex and anatomical joint form have a major impact on the development of degenerative lesions of the SIJs and their spatial distribution.

Indexed as

Sex CharacteristicsTomography, X-Ray ComputedAdultAgedAge FactorsFemaleHumansMaleMiddle AgedSacroiliac Joint

Identifiers

PMID33723315
PMCPMC7960989
OpenAlexW3136886983

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.