Evidence map›Paper›PMID 33722894›Full record

ArticleAntimicrobial agents and chemotherapy2021

Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance.

Romila Moirangthem, Kundan Kumar, Rupinder Kaur

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Does the use of topical azoles have an impact on antifungal resistance?The Journal of antimicrobial chemotherapy · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Genetic engineering in diatoms: advances and prospects.The Plant journal : for cell and molecular biology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. HPathogens (Basel, Switzerland) · 2024
    Review
  11. Review
  12. Article
  13. Molecular mechanisms governing antifungal drug resistance.npj antimicrobials and resistance · 2023
    Review
  14. Epigenetic Regulation of Antifungal Drug Resistance.Journal of fungi (Basel, Switzerland) · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Romila Moirangthem *Laboratory of Fungal Pathogenesis, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
Kundan Kumar *Laboratory of Fungal Pathogenesis, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
Rupinder KaurLaboratory of Fungal Pathogenesis, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India rkaur@cdfd.org.in.ORCID 0000-0003-3287-1700
Centre for DNA Fingerprinting and Diagnostics · INManipal Academy of Higher Education · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Increasing resistance to antifungal therapy is an impediment to the effective treatment of fungal infections.

Indexed as

Antifungal AgentsAzolesATP-Binding Cassette TransportersCandida glabrataDrug Resistance, FungalFluconazoleFungal ProteinsGene Expression Regulation, FungalGenes, MDRHumansTacrolimusTacrolimus Binding ProteinsAntifungal AgentsATP-Binding Cassette TransportersAzolesFluconazoleFungal ProteinsTacrolimusTacrolimus Binding Proteinsantifungal drug resistanceFK506-binding proteinH3K36me3histone chaperoneshistone H3 lysine 36 methylationhistone modificationshuman fungal pathogensmultidrug efflux pump expression

Identifiers

PMID33722894
PMCPMC8316114
OpenAlexW3136403098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.