Evidence map›Paper›PMID 33722886›Full record

ArticleAntimicrobial agents and chemotherapy2021

Manogepix, the Active Moiety of the Investigational Agent Fosmanogepix, Demonstrates

Hamid Badali, Hoja P Patterson, Carmita J Sanders, Barbara Mermella, Connie F C Gibas, Ashraf S Ibrahim, Karen J Shaw, Nathan P Wiederhold

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. New Perspectives on Antimicrobial Agents: Fosmanogepix.Antimicrobial agents and chemotherapy · 2026
    Review
  4. Article
  5. Fungal Meningitis in US Patients Who Received Epidural Anesthesia in Matamoros, Mexico.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  6. Medical mycology case reports · 2026
    Article
  7. Article
  8. Non-JHLT open · 2025
    Review
  9. Antimicrobial agents and chemotherapy · 2025
    Article
  10. Current Trends in Clinical Trials of Prodrugs.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  11. Fusariosis in the Sphere.Open forum infectious diseases · 2024
    Article
  12. Review
  13. Invasive fusariosis.Clinical microbiology reviews · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. New Perspectives on Antimicrobial Agents: Isavuconazole.Antimicrobial agents and chemotherapy · 2022
    Review
  19. Phylogenetic relationship ofIranian journal of microbiology · 2022
    Article
  20. Microbiology spectrum · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hamid BadaliThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Hoja P PattersonThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Carmita J SandersThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Barbara MermellaThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Connie F C GibasThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Ashraf S IbrahimThe Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Karen J ShawHearts Consulting, San Diego, California, USA.
Nathan P WiederholdThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA wiederholdn@uthscsa.edu.ORCID 0000-0002-2225-5122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the

Indexed as

FusariumAminopyridinesAntifungal AgentsIsoxazolesMicrobial Sensitivity TestsAminopyridinesAntifungal AgentsAPX001AIsoxazolesfosmanogepixFusariumFusarium oxysporumFusarium solaniin vitro activitymanogepixminimum effective concentrationsusceptibility

Identifiers

PMID33722886
PMCPMC8315997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.