Evidence map›Paper›PMID 33722883›Full record

ArticleAntimicrobial agents and chemotherapy2021

A Yeast-Based Drug Discovery Platform To Identify Plasmodium falciparum Type II NADH Dehydrogenase Inhibitors.

Yu Cao, Chen Sun, Han Wen, Mengfei Wang, Pan Zhu, Mengjiao Zhong, Jian Li, Xuewei Chen, Yefeng Tang, Jingwen Wang and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Targeting Mitochondrial Function inInternational journal of molecular sciences · 2025
    Review
  2. Inhibitors of Type II NADH Dehydrogenase Enzyme: A Review.Current protein & peptide science · 2025
    Review
  3. Article
  4. Microbiology spectrum · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yu Cao *State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Chen Sun *State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Han Wen *Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Mengfei WangMinistry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Pan ZhuState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Mengjiao ZhongState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Jian LiState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China.
Xuewei ChenSchool of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
Yefeng TangSchool of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
Jingwen WangMinistry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China jingwenwang@fudan.edu.cn zhoubing@mail.tsinghua.edu.cn.ORCID 0000-0002-6794-2604
Bing ZhouState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, China jingwenwang@fudan.edu.cn zhoubing@mail.tsinghua.edu.cn.ORCID 0000-0002-6585-9284
Tsinghua University · CNFudan University · CNCenter for Life Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional methods utilizing

Indexed as

AntimalarialsMalariaMalaria, FalciparumAnimalsDrug DiscoveryNADH DehydrogenasePlasmodium falciparumSaccharomyces cerevisiaeAntimalarialsNADH DehydrogenaseantimalarialmalariaPfNDH2PichiaPlasmodium

Identifiers

PMID33722883
PMCPMC8316042
OpenAlexW3136419060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.