ReviewJournal of neurology, neurosurgery, and psychiatry2021
Decade of progress in motor functional neurological disorder: continuing the momentum.
Review in Journal of neurology, neurosurgery, and psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Telemedicine on Health Outcomes (Clinical, Humanistic, Economic) in the Management of Patients With Functional Motor Disorder: Randomised Controlled Clinical Trial
Effectiveness of Immersive Virtual Reality Rehabilitation Program to Reduce Symptoms Severity and Improve Quality of Life in Patients With Functional Motor Disorders
Implementing a Digital Telerehabilitation Protocol and Non-motor Outcomes, and Quality of Life in Patients With Functional Motor Disorders: a Feasibility 2-arm Parallel Randomized Controlled Clinical Trial
Who cites it
66 citing papers in PubMed, 134 citations in OpenAlex.
- Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study.CNS drugs · 2026Trial
- Clinical outcomes and economic impact of a digital telemedicine intervention in patients with functional motor disorders: a single-blind, randomised controlled trial.Journal of neurology, neurosurgery, and psychiatry · 2025Trial
- Personality Disorders in Functional and Idiopathic Dystonia.Journal of clinical medicine · 2026Article
- Disrupted neural response timing and duration during hand movement preparation in schizophrenia spectrum disorder: An fMRI study.Scientific reports · 2026Article
- Functional Connectivity Gradients Reveal Altered Hierarchical Cortical Organization in Functional Neurological Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Identification and Evaluation of the Additional Effect of Cognitive Training in Balance Physiotherapy.Journal of frailty, sarcopenia and falls · 2026Review
- Emerging Trends in Functional Movement Disorders Consultations and the Impact of a Major Life Event.Movement disorders clinical practice · 2026Article
- The Effectiveness of Brief Multidisciplinary Outpatient Treatment for Functional Neurological Disorder: A Pilot Study.Physiotherapy Canada. Physiotherapie Canada · 2026Article
- Exploring the autism and functional neurological disorder association: Considerations from biopsychosocial, neuropsychological and computational models.Autism : the international journal of research and practice · 2026Review
- Functional sensory symptoms and signs: a case-control study of 102 patients.Brain communications · 2026Article
- Relationships between brain functional connectivity and resting cardiac autonomic profiles in functional neurological disorder: A pilot study.NeuroImage. Clinical · 2026Article
- Electroclinical Dissociation in Generalized Epilepsy: A Video-EEG Case From Sub-Saharan Africa.Case reports in medicine · 2026Article
- Reduced intracortical inhibition and enhanced intracortical facilitation in patients with functional tremor.BMJ neurology open · 2026Article
- Stress-related neuroplasticity and developmental vulnerability in functional neurological disorder: from adverse experience to maladaptive overlearning.Frontiers in molecular neuroscience · 2026Review
- Momentary predictors of dissociation in functional neurological disorder: an ecological momentary assessment-based pilot study.Frontiers in psychiatry · 2026Article
- Uncertainty as an operative construct and treatment target in functional neurological disorder.Frontiers in psychiatry · 2026Article
- Inpatient cognitive analytic therapy for functional neurological disorder: A mixed methods four-phase single-case experimental design.Psychology and psychotherapy · 2025Article
- Unraveling functional neurological disorder in pediatric populations: A systematic review of diagnosis, treatment, and outcomes.World journal of clinical pediatrics · 2025Article
- Functional Movement Disorder: Evolving Mechanisms, Diagnostic Precision, and Personalized Multidisciplinary Care.Movement disorders clinical practice · 2025Review
- Current Opinions and Practices in Functional Neurological Disorders: A Survey of Indian Neurologists.Annals of Indian Academy of Neurology · 2025Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
Abstract
Functional neurological disorder (FND) is a prevalent, disabling and costly condition at the neurology-psychiatry intersection. After being marginalised in the late 20th century, there has been renewed interest in this field. In this article, we review advances that have occurred over the past decade (2011-2020) across diagnosis, mechanisms, aetiologies, treatments and stigma in patients with motor FND (mFND, that is, functional movement disorder and functional limb weakness). In each content area, we also discuss the implications of recent advances and suggest future directions that will help continue the momentum of the past decade. In diagnosis, a major advance has been the emphasis on rule-in physical signs that are specific for hyperkinetic and hypokinetic functional motor symptoms. Mechanistically, greater importance has been given to determining 'how' functional neurological symptoms develop, highlighting roles for misdirected attention, expectation and self-agency, as well as abnormal influences of emotion/threat processing brain areas on motor control circuits. Aetiologically, while roles for adverse life experiences remain of interest in mFND, there is recognition of other aetiologic contributors, and efforts are needed to investigate links between aetiological factors and mechanisms. This decade has seen the first randomised controlled trials for physiotherapy, multidisciplinary rehabilitation and psychotherapy performed in the field, with consensus recommendations for physiotherapy, occupational therapy and outcome measures also published. Across patients, clinicians, healthcare systems and society, stigma remains a major concern. While challenges persist, a patient-centred integrated clinical neuroscience approach is primed to carry forward the momentum of the past decade into the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.