Evidence map›Paper›PMID 33722805›Full record

Trial reportBMJ open gastroenterology2021

Endoscopic treatment of Crohn-related strictures with a self-expandable stent compared with balloon dilation: a prospective, randomised, controlled study.

Per Hedenström, Per-Ove Stotzer

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04718493 nacompletednot on this map

Endoscopic Stenting in Crohn Related Strictures

TypeinterventionalSponsorSahlgrenska University HospitalRan2013 to 2020Enrolled13ConditionsIntestinal Strictures Related to Crohn´s DiseaseArmsSelf-expandable metal stent, Balloon dilatation
NCT06725563 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Endoscopically Placed Lumen-Apposing Metal Stents as a Safe Alternative to Surgery for the Treatment of Symptomatic Intestinal Strictures in Individuals With Inflammatory Bowel Disease

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2025 to 2026Enrolled20ConditionsInflammatory Bowel Diseases, Stricture, BowelArmsEndoscopically placed lumen-apposing metal stents for the treatment of IBD-strictures
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Endoscopic stricture management in inflammatory bowel disease: Present and future.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  3. Article
  4. Review
  5. Pediatric stricturing Crohn's disease.World journal of gastroenterology · 2024
    Article
  6. Review
  7. Article
  8. Futuristic Developments and Applications in Endoluminal Stenting.Gastroenterology research and practice · 2022
    Review
  9. Intestinal strictures in Crohn's disease: a 2021 update.Therapeutic advances in gastroenterology · 2022
    Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Per HedenströmIntitute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg University, Gothenburg, Sweden per.hedenstrom@gu.se.ORCID 0000-0002-4106-1454
Per-Ove StotzerIntitute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg University, Gothenburg, Sweden.
Sahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFibrotic strictures in the gastrointestinal tract are frequent in Crohn's disease. Endoscopic dilation is a standard treatment. However, recurrence is common after dilation and there are complications such as bleeding or perforation. Endoscopic treatment using self-expandable metal stents has shown diverging results. The aim of this study was to evaluate the outcome of endoscopic treatment with a self-expandable stent in ileocecal Crohn's disease. DESIGN/

methodPatients with Crohn's disease and a symptomatic ileocecal stricture were eligible for prospective, consecutive inclusion in a single-centre setting. Patients were randomised to treatment with either 18 mm balloon dilatation (Group

resultsThirteen patients (Group

conclusionPatients with strictures related to Crohn's disease may benefit from treatment with self-expandable metal stents rather than dilatation. However, there seems to be an increased risk for patient pain after stenting, which has to be considered and handled. TRAIL REGISTRATION NUMBER: The study was registered at Clinical Trials (NCT04718493).

Indexed as

StentsConstriction, PathologicDilatationHumansInfant, NewbornProspective StudiesRetrospective StudiesTreatment Outcomecrohn's diseaseendoscopyfibrosisstents

Identifiers

PMID33722805
PMCPMC7970316
OpenAlexW3138520118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.