Evidence map›Paper›PMID 33722804›Full record

ReviewBMJ open gastroenterology2021

Recurrent myocarditis in a patient with active ulcerative colitis: a case report and review of the literature.

Giacomo Caio, Lisa Lungaro, Fabio Caputo, Maria Muccinelli, Maria Caterina Marcello, Eleonora Zoli, Umberto Volta, Roberto De Giorgio, Giorgio Zoli

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMJ open gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Recurrent Pleuropericarditis Associated with Mesalazine Therapy Masked by Steroid Use.European journal of case reports in internal medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Mesalazine-induced myopericarditis: a case series.European heart journal. Case reports · 2023
    Article
  9. Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Review
  10. Myocarditis With Cardiogenic Shock in a Young Female With Severe Ulcerative Colitis Flare.Journal of community hospital internal medicine perspectives · 2023
    Article
  11. Article
  12. Article
  13. Acute myocarditis after a third dose of the BNT162b2 COVID-19 vaccine.Revista espanola de cardiologia (English ed.) · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Giacomo CaioDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-4244-4529
Lisa LungaroDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-9053-5671
Fabio CaputoDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Maria MuccinelliDepartment of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.
Maria Caterina MarcelloDepartment of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.
Eleonora ZoliDepartment of Internal Medicine, SS. Annunziata Hospital, Cento, University of Ferrara, Ferrara, Italy.
Umberto VoltaDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Roberto De GiorgioDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Giorgio ZoliDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy giorgio.zoli@unife.it.
University of Ferrara · ITHarvard University · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel diseases such as ulcerative colitis (UC) may be complicated by several extraintestinal manifestations. These involve joints, skin, eyes and less commonly lungs and heart. Myocarditis may result from the toxic effect of drugs (ie, mesalazine) commonly used for the treatment of UC or due to infections (eg, Coxsackieviruses, enteroviruses, adenovirus). Here, we report a case of a 26-year old man affected by UC and complicated by two episodes of myocarditis. Both episodes occurred during two severe exacerbations of UC. However, in both cases the aetiology of myocarditis remains uncertain being ascribable to extraintestinal manifestation, drug toxicity or both.

Indexed as

Colitis, UlcerativeInflammatory Bowel DiseasesMyocarditisAdultHumansMaleMesalamineMesalaminedrug toxicityIBDulcerative colitis

Identifiers

PMID33722804
PMCPMC7970288
OpenAlexW3137060279

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.