ReviewNeuroscience and biobehavioral reviews2021
Hippocampal volume and navigational ability: The map(ping) is not to scale.
Review in Neuroscience and biobehavioral reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- A Descriptive Analysis of Transient Global Amnesia-Like Cases in Open Water Swimmers.Sports medicine (Auckland, N.Z.) · 2026Article
- Deep learning approaches to map individual differences in macroscopic neural structure with variations in spatial navigation behavior.Neuropsychologia · 2026Article
- Lost before forgetting: objective driving metrics track navigation deficits tied to preclinical Alzheimer's disease.Innovation in aging · 2026Article
- Inferior and Middle Longitudinal Fasciculus and Fornix Support Allocentric Representation.Hippocampus · 2025Article
- Understanding the return journey: Determinants of route retracing in younger and older adults.Psychology and aging · 2025Article
- Navigating space and the developing mind.Frontiers in psychology · 2025Review
- Hippocampal Synaptic Plasticity: Integrating Memory and Anxiety Impairments in the Early Stages of Alzheimer's Disease.Current topics in behavioral neurosciences · 2025Review
- Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Spatial navigation and memory: A review of the similarities and differences relevant to brain models and age.Neuron · 2023Review
- The hearing hippocampus.Progress in neurobiology · 2022Review
- Temporal pole volume is associated with episodic autobiographical memory in healthy older adults.Hippocampus · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
Abstract
A critical question regards the neural basis of complex cognitive skill acquisition. One extensively studied skill is navigation, with evidence suggesting that humans vary widely in navigation abilities. Yet, data supporting the neural underpinning of these individual differences are mixed. Some evidence suggests robust structure-behavior relations between hippocampal volume and navigation ability, whereas other experiments show no such correlation. We focus on several possibilities for these discrepancies: 1) volumetric hippocampal changes are relevant only at the extreme ranges of navigational abilities; 2) hippocampal volume correlates across individuals but only for specific measures of navigation skill; 3) hippocampal volume itself does not correlate with navigation skill acquisition; connectivity patterns are more relevant. To explore this third possibility, we present a model emphasizing functional connectivity changes, particularly to extra-hippocampal structures. This class of models arises from the premise that navigation is dynamic and that good navigators flexibly solve spatial challenges. These models pave the way for research on other skills and provide more precise predictions for the neural basis of skill acquisition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.