Evidence map›Paper›PMID 33722285›Full record

ArticleParasites & vectors2021

Prevalence of scabies and impetigo in school-age children in Timor-Leste.

Alexander Matthews, Brandon Le, Salvador Amaral, Paul Arkell, Merita Monteiro, Naomi Clarke, Terlinda Barros, Joaquim de Jesus Mendonça, Sonia Maria Exposto Gusmão, Leonia Maria Dos Reis Seixas and 8 more

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Prevalence and determinants of scabies: A global systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Alexander MatthewsRoyal Darwin Hospital, Darwin, Australia. alextommatt@gmail.com.
Brandon LeThe Kirby Institute, University of New South Wales, Sydney, Australia.
Salvador AmaralMenzies School of Health Research, Charles Darwin University, Darwin, Australia.
Paul ArkellMenzies School of Health Research, Charles Darwin University, Darwin, Australia.
Merita MonteiroTimor-Leste Ministry of Health, Dili, Timor-Leste.
Naomi ClarkeThe Kirby Institute, University of New South Wales, Sydney, Australia.
Terlinda BarrosHospital Nacional Guido Valadares, Dili, Timor-Leste.
Joaquim de Jesus MendonçaHospital Nacional Guido Valadares, Dili, Timor-Leste.
Sonia Maria Exposto GusmãoHospital Nacional Guido Valadares, Dili, Timor-Leste.
Leonia Maria Dos Reis SeixasHospital Nacional Guido Valadares, Dili, Timor-Leste.
João Henrique Araújo da PiedadeHospital Nacional Guido Valadares, Dili, Timor-Leste.
Daniel EngelmanTropical Diseases, Murdoch Children's Research Institute, Melbourne, Australia.
Andrew C SteerTropical Diseases, Murdoch Children's Research Institute, Melbourne, Australia.
Nicholas S S FancourtRoyal Darwin Hospital, Darwin, Australia.
Jennifer YanRoyal Darwin Hospital, Darwin, Australia.
John KaldorThe Kirby Institute, University of New South Wales, Sydney, Australia.
Joshua R Francis *Royal Darwin Hospital, Darwin, Australia.
Susana Vaz Nery *The Kirby Institute, University of New South Wales, Sydney, Australia.
Universidade da Paz · TLUNSW Sydney · AUCharles Darwin University · AUMenzies School of Health Research · AUMurdoch Children's Research Institute · AURoyal Darwin Hospital · AU

Funding

Department of Foreign Affairs and Trade, Australian Government Indo Pacific Centre for Health Security APP1152979National Health and Medical Research Council Centre for Research Excellence APP1153727
6 · The paper itself

Abstract

backgroundScabies and impetigo are endemic in many tropical, low- and middle-income countries. Mass drug administration (MDA) with ivermectin has emerged as a control strategy for these conditions. In 2019, Timor-Leste Ministry of Health planned to implement MDA including ivermectin for the control of lymphatic filariasis, so we undertook a baseline assessment of scabies and impetigo to better understand local epidemiology and contribute to future surveys assessing the impact of MDA.

methodsA cross-sectional school survey was conducted in April-May 2019 at six primary schools in a semi-urban (Dili) and two rural (Ermera and Manufahi) settings. Children under 19 years of age present at school on survey days were eligible to participate, of whom we enrolled 1183. Trained health workers interviewed and examined 1043 participants to clinically diagnose scabies using the 2020 International Alliance for the Control of Scabies (IACS) diagnostic criteria, as well as impetigo. Prevalence was adjusted for age and sex. Mixed-effects logistic regression models were used to analyse odds of scabies and impetigo infection. All models accounted for clustering at the school level through the use of random effect terms. Population attributable risk of scabies as a cause of impetigo was also estimated.

resultsThe overall weighted prevalence of scabies was 30.6%. Children in rural Manufahi were more likely to have scabies than those in semi-urban Dili (53.6% vs 28.2%, adjusted odds ratio [AOR] 3.5). Most cases of scabies were mild (3 to 10 lesions), and lesions were usually distributed on more than one body region. Scabies prevalence was lower among 10 to 14 year olds compared to 5 to 9 year olds. Overall weighted prevalence of impetigo was 11.3%. Relative to Dili, children in rural Ermera and Manufahi were twice as likely to have impetigo. Impetigo was twice as common in children with scabies than in those without, corresponding to an attributable risk of scabies as a cause of impetigo of 22.7%.

conclusionsScabies and impetigo prevalence in Timor-Leste is among the highest reported globally, particularly in rural areas. Scabies infestation was strongly associated with impetigo. Comprehensive control strategies are urgently needed in Timor-Leste.

Indexed as

PopulationAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansImpetigoInfantInfant, NewbornLogistic ModelsMaleOdds RatioPrevalenceRisk FactorsRural PopulationChildrenImpetigoScabiesTimor-Leste

Identifiers

PMID33722285
PMCPMC7962383
OpenAlexW3112480079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.