ArticlePituitary2021
Gut microbiota in patients with newly diagnosed acromegaly: a pilot cross-sectional study.
Article in Pituitary, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 19 citations in OpenAlex.
- Acromegaly and colorectal cancer risk: emerging roles of the gut microbiota.Frontiers in endocrinology · 2026Review
- Oral and gut microbiota after acromegaly treatment: prospective assessment and insights from machine learning.Pituitary · 2025Article
- Causal relationship between gut microbiota and pituitary neuroendocrine tumors: a bidirectional Mendelian randomization.Discover oncology · 2025Article
- Unveiling gut microbiome divergence in sellar-parasellar masses and brain tumors: A link beyond the skull.Neurosurgical review · 2025Article
- Microbiome and metabolic disorder in prolactinoma: intrinsic gender differences and extrinsic therapy effects.Pituitary · 2025Article
- Exploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.Frontiers in microbiology · 2025Article
- The comprehensive evaluation of oral and fecal microbiota in patients with acromegaly.Pituitary · 2024Article
- Article
- Impact of different growth hormone levels on gut microbiota and metabolism in short stature.Pediatric research · 2024Article
- Revealing the link between gut microbiota and brain tumor risk: a new perspective from Mendelian randomization.Frontiers in cellular and infection microbiology · 2024Article
- Gut microbiota in brain tumors: An emerging crucial player.CNS neuroscience & therapeutics · 2023Review
- PitNETs and the gut microbiota: potential connections, future directions.Frontiers in endocrinology · 2023Review
- Circulating microbiota and metabolites: Insights into cardiovascular diseases.Journal of clinical laboratory analysis · 2022Review
- Excess Growth Hormone Alters the Male Mouse Gut Microbiome in an Age-dependent Manner.Endocrinology · 2022Article
- Article
- Exploring blood microbial communities and their influence on human cardiovascular disease.Journal of clinical laboratory analysis · 2022Review
- Characteristics of Gut Microbiota in Patients with GH-Secreting Pituitary Adenoma.Microbiology spectrum · 2022Article
- Alterations of the Gut Microbiome in Patients With Pituitary Adenoma.Pathology oncology research : POR · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMicrobiota has crucial biological importance for human well-being. Bidirectional interaction exists between microbiota and the host, and there have been no studies investigating this interaction in patients with acromegaly. We aimed to analyze the composition of microbiota in patients with newly diagnosed acromegaly.
methodStool samples were obtained from the patients with newly diagnosed acromegaly in the Endocrinology Clinic of Erciyes University Medical School. The composition of microbiota was analyzed, and the results were compared to healthy volunteers matched to the patients in terms of age, gender and body mass index.
resultsSeven patients (three male, four female) with a mean age of 48 ± 17.6 years were included in the study. The stool analysis revealed a significantly lower bacterial diversity in the patients with acromegaly. Bacteroidetes phylum was predominating in the patient group, and Firmicutes/Bacteroidetes ratio was altered significantly. Bifidobacterium, Collinsella, Bacteroides, Butyricimonas, Clostridium, Oscillospira, and Dialister were predominating in the control group.
conclusionThe gut microbiota is significantly altered in patients with newly diagnosed acromegaly. Further prospective studies are needed to elucidate the causative relationship between acromegaly, colorectal pathologies, and microbial alterations.
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