Evidence map›Paper›PMID 33721074›Full record

SynthesisWorld journal of surgery2021

Blumgart Anastomosis After Pancreaticoduodenectomy. A Comprehensive Systematic Review, Meta-Analysis, and Meta-Regression.

Claudio Ricci, Carlo Ingaldi, Laura Alberici, Nico Pagano, Cristina Mosconi, Giovanni Marasco, Francesco Minni, Riccardo Casadei

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pancreaticojejunostomy Conducive to Biological Healing in Minimally Invasive Pancreaticoduodenectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Review
  10. Article
  11. Pancreatic cancer in 2021: What you need to know to win.World journal of gastroenterology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudio RicciDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy. claudiochir@gmail.com.
Carlo IngaldiDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy.
Laura AlbericiDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy.
Nico PaganoDivision of Gastroenterology, Azienda Ospedaliero-Universitaria Di Bologna, via Albertoni 15, Bologna, Italia.
Cristina MosconiDivision of Radiology, Azienda Ospedaliero-Universitaria Di Bologna, via Albertoni 15, Bologna, Italia.
Giovanni MarascoDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy.
Francesco MinniDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy.
Riccardo CasadeiDepartment of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, , S.Orsola-Malpighi Hospital, University of Bologna, Policlinico S.Orsola-Malpighi Via Massarenti n.9, 40138, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe superiority of Blumgart anastomosis (BA) over non-BA duct to mucosa (non-BA DtoM) still remains under debate.

methodsWe performed a systematic search of studies comparing BA to non-BA DtoM. The primary endpoint was CR-POPF. Postoperative morbidity and mortality, post-pancreatectomy hemorrhage (PPH), delayed gastric emptying (DGE), reoperation rate, and length of stay (LOS) were evaluated as secondary endpoints. The meta-analysis was carried out using random effect. The results were reported as odds ratio (OR), risk difference (RD), weighted mean difference (WMD), and number needed to treat (NNT).

resultsTwelve papers involving 2368 patients: 1075 BA and 1193 non-BA DtoM were included. Regarding the primary endpoint, BA was superior to non-BA DtoM (RD = 0.10; 95% CI: -0.16 to -0.04; NNT = 9). The multivariate ORs' meta-analysis confirmed BA's protective role (OR 0.26; 95% CI: 0.09 to 0.79). BA was superior to DtoM regarding overall morbidity (RD = -0.10; 95% CI: -0.18 to -0.02; NNT = 25), PPH (RD = -0.03; 95% CI -0.06 to -0.01; NNT = 33), and LOS (- 4.2 days; -7.1 to -1.2 95% CI).

conclusionBA seems to be superior to non-BA DtoM in avoiding CR-POPF.

Indexed as

PancreatectomyPancreaticoduodenectomyAnastomosis, SurgicalHumansPancreatic FistulaPostoperative ComplicationsReoperation

Identifiers

PMID33721074
PMCPMC8093149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.