Evidence map›Paper›PMID 33721057›Full record

ReviewDer Pathologe2021

Cooperative approach of pathology and neuropathology in the COVID-19 pandemic : German registry for COVID-19 autopsies (DeRegCOVID) and German network for autopsies in pandemics (DEFEAT PANDEMIcs).

Saskia von Stillfried, Till Acker, Martin Aepfelbacher, Gustavo Baretton, Roman David Bülow, Karl-Friedrich Bürrig, Hans-Ulrich Holtherm, Danny Jonigk, Ruth Knüchel, Raphael W Majeed and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Der Pathologe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?Virchows Archiv : an international journal of pathology · 2022
    Review
  2. Complement ActivationFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Saskia von StillfriedInstitute of Pathology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany. svonstillfri@ukaachen.de.
Till AckerInstitute of Neuropathology, Justus-Liebig University Giessen, Giessen, Germany.
Martin AepfelbacherInstitute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Gustavo BarettonInstitute of Pathology, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.
Roman David BülowInstitute of Pathology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Karl-Friedrich BürrigInstitute of Pathology Hildesheim, Hildesheim, Germany.
Hans-Ulrich HolthermFederal Ministry of Health, Berlin, Germany.
Danny JonigkHannover Medical School, German Lung Research Center Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), Hannover, Germany.
Ruth KnüchelInstitute of Pathology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.
Raphael W MajeedInstitute for Medical Informatics, University Hospital RWTH Aachen University, Aachen, Germany.
Rainer RöhrigInstitute for Medical Informatics, University Hospital RWTH Aachen University, Aachen, Germany.
Jan WienströerInstitute for Medical Informatics, University Hospital RWTH Aachen University, Aachen, Germany.
Peter BoorInstitute of Pathology, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany. pboor@ukaachen.de.
RWTH Aachen University · DEFederal Ministry of Health · DEGerman Center for Lung Research · DEJustus-Liebig-Universität Gießen · DEUniversität Hamburg · DEUniversitätsklinikum Aachen · DEUniversity Hospital Carl Gustav Carus · DEUniversity of Hildesheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutopsy is an important tool for understanding the pathogenesis of diseases, including COVID-19. MATERIAL AND

methodsOn 15 April 2020, together with the German Society of Pathology and the Federal Association of German Pathologists, the German Registry of COVID-19 Autopsies (DeRegCOVID) was launched ( www.DeRegCOVID.ukaachen.de ). Building on this, the German Network for Autopsies in Pandemics (DEFEAT PANDEMIcs) was established on 1 September 2020.

resultsThe main goal of DeRegCOVID is to collect and distribute de facto anonymized data on potentially all autopsies of people who have died from COVID-19 in Germany in order to meet the need for centralized, coordinated, and structured data collection and reporting during the pandemic. The success of the registry strongly depends on the willingness of the respective centers to report the data, which has developed very positively so far and requires special thanks to all participating centers. The rights to own data and biomaterials (stored decentrally) remain with each respective center. The DEFEAT PANDEMIcs network expands on this and aims to strengthen harmonization and standardization as well as nationwide implementation and cooperation in the field of pandemic autopsies.

conclusionsThe extraordinary cooperation in the field of autopsies in Germany during the COVID-19 pandemic is impressively demonstrated by the establishment of DeRegCOVID, the merger of the registry of neuropathology (CNS-COVID19) with DeRegCOVID and the establishment of the autopsy network DEFEAT PANDEMIcs. It gives a strong signal for the necessity, readiness, and expertise to jointly help manage current and future pandemics by autopsy-derived knowledge.

Indexed as

COVID-19PandemicsAutopsyHumansRegistriesSARS-CoV-2AutopsyInteroperabilityRegistriesSARS-CoV‑2Tissue banks

Identifiers

PMID33721057
PMCPMC7958937
OpenAlexW3129402799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.