ArticleMedical science monitor : international medical journal of experimental and clinical research2021
Risk Factors and Safety Analyses for Intrapartum Fever in Pregnant Women Receiving Epidural Analgesia During Labor.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The effect of intrapartum maternal fever on neonatal outcomes: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Epidural-Related Fever and Cesarean Delivery: Comparing Ropivacaine/Dexmedetomidine and Ropivacaine/Sufentanil: A Single-Center Randomized Controlled Study in 695 Women.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Efficacy of Intravenous Butorphanol for Preventing Epidural-Related Maternal Fever (ERMF) During Epidural Labor Analgesia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.Drug design, development and therapy · 2025Trial
- Assessing Postpartum Readmission Rates and Associated Risk Factors Using the Robson Classification: A Single-Center Experience.Journal of clinical medicine · 2026Article
- Relatively low plasma cortisol levels in parturients are associated with epidural-related maternal fever.Annals of medicine · 2025Article
- Development and validation of a machine learning model for predicting intrapartum fever using pre-labor analgesia clinical indicators: a multicenter retrospective study.BMC pregnancy and childbirth · 2025Article
- Machine Learning-Driven Intrapartum Fever Prediction: A Comprehensive Large Retrospective Cohort Study Integrating Inflammatory and Obstetric Markers.International journal of general medicine · 2025Article
- Machine learning algorithms to predict epidural-related maternal fever: a retrospective study.Frontiers in pharmacology · 2025Article
- Development of a Machine Learning Model to Predict Epidural-Related Maternal Fever During Labor Analgesia: A Multi-Algorithm Comparative Study with Prospective Implementation Framework.International journal of women's health · 2025Article
- Role of mitochondrial DNA level in epidural-related maternal fever: a single-centre, observational, pilot study.BMC pregnancy and childbirth · 2024Observational
- Clinical effect of different concentrations of ropivacaine in the labor analgesia of dural puncture epidural technique for obese puerperae.Perioperative medicine (London, England) · 2024Article
- Article
- Combined spinal-epidural analgesia and epidural analgesia induced maternal fever with a similar timing during labor-A randomized controlled clinical trial.Frontiers in medicine · 2022Article
- Retrospective study of intrapartum fever in term pregnancies and adverse obstetric and neonatal outcomes.PeerJ · 2022Article
- Intrathecal Injection of Ropivacaine Reduces Cervical Resistance in Late-Pregnant Rats.Drug design, development and therapy · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND We aimed to explore the factors leading to epidural-related maternal fever and the influence of intrapartum fever on neonates. MATERIAL AND METHODS A retrospective analysis was performed on data from pregnant women who received epidural analgesia during labor. The primary aim was to determine the influence of epidural labor analgesia on the incidence of intrapartum fever in pregnant women. The secondary aim was to determine the influence of intrapartum fever on neonates. RESULTS Logistic regression analysis showed that premature rupture of membranes (OR=2.008, 95% CI: 1.551-2.600), vaginal examination performed more than 6 times (OR=1.681, 95% CI: 1.286-2.197), long duration of labor (OR=1.090, 95% CI: 1.063-1.118), and long time from rupture of membranes to delivery (OR=1.048, 95% CI: 1.010-1.087) were all risk factors for intrapartum fever in pregnant women with epidural labor analgesia. Regarding the secondary research outcome, the incidence of intrapartum fever was significantly associated with the number of neonates with Apgar score of 10 delivered from pregnant women with epidural labor analgesia (P<0.05). There was no statistically significant difference in the transfer rate of newborns to the Neonatal Intensive Care Unit (NICU) (P>0.05). CONCLUSIONS Premature rupture of membranes, vaginal examination performed more than 6 times, long duration of labor, and long time from rupture of membranes to delivery are all factors raising the risk of fever during epidural labor analgesia. Although intrapartum fever in the mothers had a significant influence on the number of neonates with Apgar score of 10, it did not affect the outcome of neonates in terms of NICU transfer rate.
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