ArticleJCO clinical cancer informatics2021
OSIRIS: A Minimum Data Set for Data Sharing and Interoperability in Oncology.
Article in JCO clinical cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Leveraging Real-World Data for Clinical Decision Making in Geriatric Oncology.Drugs & aging · 2026Review
- The cost-effectiveness of medical versus surgical androgen deprivation therapy for advanced prostate cancer in Tanzania: a Markov model-based analysis.Frontiers in public health · 2026Article
- The ICGC ARGO data dictionary for standardizing global cancer clinical data.Scientific data · 2025Article
- Informatics at the Frontier of Cancer Research.Cancer research · 2025Review
- Making the case for an International Childhood Cancer Data Partnership.Journal of the National Cancer Institute · 2025Article
- Challenges of data quality for the management of prostate cancer in Tanzania: A hurdle towards improving the quality of service.PLOS global public health · 2025Article
- Development of a Secure Web-Based Medical Imaging Analysis Platform: The AWESOMME Project.Journal of imaging informatics in medicine · 2024Article
- The 1+Million Genomes Minimal Dataset for Cancer.Nature genetics · 2024Article
- Consore: A Powerful Federated Data Mining Tool Driving a French Research Network to Accelerate Cancer Research.International journal of environmental research and public health · 2024Article
- UNCAN.eu: Toward a European Federated Cancer Research Data Hub.Cancer discovery · 2024Article
- From data strategy to implementation to advance cancer research and cancer care: A French comprehensive cancer center experience.PLOS digital health · 2023Article
- Clinical Informatics Approaches to Facilitate Cancer Data Sharing.Yearbook of medical informatics · 2023Review
- A Digital Solution for an Advanced Breast Tumor Board: Pilot Application Cocreation and Implementation Study.JMIR cancer · 2023Article
- Precision Oncology Core Data Model to Support Clinical Genomics Decision Making.JCO clinical cancer informatics · 2023Article
- Opportunities and Obstacles to the Development of Health Data Warehouses in Hospitals in France: The Recent Experience of Comprehensive Cancer Centers.International journal of environmental research and public health · 2023Review
- HL7 FHIR-based tools and initiatives to support clinical research: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Clinical annotations for prostate cancer research: Defining data elements, creating a reproducible analytical pipeline, and assessing data quality.The Prostate · 2022Observational
- Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review.JMIR medical informatics · 2022Review
- A knowledge graph representation of baseline characteristics for the Dutch proton therapy research registry.Clinical and translational radiation oncology · 2021Article
Corrections and comments
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Authors and funding
16 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMany institutions throughout the world have launched precision medicine initiatives in oncology, and a large amount of clinical and genomic data is being produced. Although there have been attempts at data sharing with the community, initiatives are still limited. In this context, a French task force composed of Integrated Cancer Research Sites (SIRICs), comprehensive cancer centers from the Unicancer network (one of Europe's largest cancer research organization), and university hospitals launched an initiative to improve and accelerate retrospective and prospective clinical and genomic data sharing in oncology. MATERIALS AND
methodsFor 5 years, the OSIRIS group has worked on structuring data and identifying technical solutions for collecting and sharing them. The group used a multidisciplinary approach that included weekly scientific and technical meetings over several months to foster a national consensus on a minimal data set.
resultsThe resulting OSIRIS set and event-based data model, which is able to capture the disease course, was built with 67 clinical and 65 omics items. The group made it compatible with the HL7 Fast Healthcare Interoperability Resources (FHIR) format to maximize interoperability. The OSIRIS set was reviewed, approved by a National Plan Strategic Committee, and freely released to the community. A proof-of-concept study was carried out to put the OSIRIS set and Common Data Model into practice using a cohort of 300 patients.
conclusionUsing a national and bottom-up approach, the OSIRIS group has defined a model including a minimal set of clinical and genomic data that can be used to accelerate data sharing produced in oncology. The model relies on clear and formally defined terminologies and, as such, may also benefit the larger international community.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.