Evidence map›Paper›PMID 33719913›Full record

ArticleAJOB empirical bioethics

Reframing Recruitment: Evaluating Framing in Authorization for Research Contact Programs.

Candace D Speight, Charlie Gregor, Yi-An Ko, Stephanie A Kraft, Andrea R Mitchell, Nyiramugisha K Niyibizi, Bradley G Phillips, Kathryn M Porter, Seema K Shah, Jeremy Sugarman and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJOB empirical bioethics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Public attitudes toward an authorization for contact program for clinical research.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Candace D SpeightEmory University, School of Medicine, Atlanta, Georgia, USA.
Charlie GregorSchool of Medicine, Dean's Office, Institute of Translational Health Sciences, Seattle, Washington, USA.ORCID 0000-0002-9184-2910
Yi-An KoDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Stephanie A KraftTreuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0002-2862-7601
Andrea R MitchellEmory University, School of Medicine, Atlanta, Georgia, USA.
Nyiramugisha K NiyibiziEmory University, School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0001-8303-0405
Bradley G PhillipsUniversity of Georgia College of Pharmacy, Athens, Georgia, USA.
Kathryn M PorterTreuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID 0000-0003-1930-9625
Seema K ShahDepartment of Pediatrics, School of Medicine, Northwestern University Feinberg, Chicago, Illinois, USA.
Jeremy SugarmanBerman Institute of Bioethics & Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-7022-8332
Benjamin S WilfondTreuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, Washington, USA.
Neal W DickertEmory University, School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0003-4415-3861

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002319NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

backgroundThe changing clinical research recruitment landscape involves practical challenges but introduces opportunities. Researchers can now identify large numbers of eligible patients through electronic health record review and can directly contact those who have authorized contact. Applying behavioral science-driven strategies to design and frame communication could affect patients' willingness to authorize contact and their understanding of these programs. The ethical and practical implications of various strategies warrant empirical evaluation.

methodsWe conducted an online survey (

resultsCompared to the neutral flyer, individuals who received the positive text flyer were numerically more likely to enroll, but this was not statistically significant (24.2% v. 19.0%,

conclusionsThis study demonstrated that employing behavioral science-driven communication strategies for authorization for research contact had an effect on likelihood of hypothetical enrollment but did not significantly affect comprehension. Strategies using simple, positive language and visual tools may be effective and ethically appropriate. Further studies should explore how these and other approaches can help to optimize research recruitment.

Indexed as

CommunicationElectronic Health RecordsHumansSurveys and Questionnairesclinical researchelectronic health recordsInformed consentrecruitmentresearch ethicssurvey

Identifiers

PMID33719913
PMCPMC10788686

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.