Evidence map›Paper›PMID 33719664›Full record

ArticleJDR clinical and translational research2022

Social, Psychological, and Behavioral Predictors of Salivary Bacteria, Yeast in Caries-Free Children.

D T Kopycka-Kedzierawski, K Scott-Anne, P G Ragusa, M Cvetanovska, K Flint, C Feng, G E Watson, C L Wong, R J Billings, R J Quivey and 1 more

Open access · greenAbstract read
In one paragraph

Article in JDR clinical and translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Primary tooth emergence in young children is associated with a stress biomarker.Journal of developmental origins of health and disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

D T Kopycka-KedzierawskiDepartment of Dentistry and Center for Oral Biology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-0798-6805
K Scott-AnneCenter for Oral Biology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
P G RagusaDepartment of Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
M CvetanovskaDepartment of Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
K FlintDepartment of Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
C FengDepartment of Biostatistics and Computational Biology and Department of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, NY, USA.
G E WatsonDepartment of Dentistry and Center for Oral Biology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
C L WongDepartment of Pediatric Dentistry and Pediatrics, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
R J BillingsDepartment of Dentistry and Center for Oral Biology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
R J QuiveyCenter for Oral Biology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
T G O'ConnorDepartments of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, University of Rochester, Rochester, NY, USA.
Eastman Chemical Company (United States) · USUniversity of Rochester · US

Funding

Integrating Oral Biology and Behavioral and Social Mechanisms for ECC OnsetR01DE024985 · NIDCR · UNIVERSITY OF ROCHESTER · PI KOPYCKA-KEDZIERAWSKI, DOROTA T. · 2015 to 2019
$3.5M
NIDCR NIH HHS R01 DE024985
6 · The paper itself

Abstract

introductionEarly childhood caries (ECC) is a complex, multifactorial oral disease that is a major public health concern because it is prevalent, profoundly alters a child's quality of life, is difficult to treat effectively, and has a distressing tendency to recur following treatment.

objectivesThe purpose of the study was to examine social, psychological, and behavioral predictors of salivary bacteria and yeast in young children at risk for ECC.

methodsA sample of 189 initially caries-free preschool children was assessed for child stress physiology from salivary cortisol, child and family stress exposure, diet, oral health behaviors, and sociodemographic risks. Multiple logistic regression analysis was implemented to examine the associations between these risk factors and cariogenic microorganisms: mutans streptococci (MS), lactobacilli (LB), and

resultsHigher baseline salivary cortisol (odds ratio [OR] = 6.26; 95% confidence level [CL], 1.69-23.16) and a blunted response to an acute laboratory stressor (OR = .56; 95% CL, .37-.83) were associated with an increased likelihood of elevated salivary MS (≥10

conclusionsThe impact of sociodemographic risk and stress physiology on cariogenic disease processes are evident prior to ECC onset. The findings provide novel data on the early onset of cariogenic processes in children and the importance of considering sociodemographic, psychosocial, and behavioral factors when judging ECC risk. KNOWLEDGE TRANSFER STATEMENT: The findings provide valuable and novel findings that, pre-ECC onset, the caries disease process is explicable from a detailed assessment of behavioral, sociodemographic, and psychosocial stress variables.

Indexed as

Dental CariesSaccharomyces cerevisiaeChild, PreschoolHumansHydrocortisoneLactobacillusQuality of LifeSalivaStreptococcus mutansHydrocortisoneCandidaearly childhood caries riskLactobacilluspreschool childrensalivary cortisolStreptococcus mutans

Identifiers

PMID33719664
PMCPMC8928412
OpenAlexW3134828332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.