Evidence map›Paper›PMID 33719572›Full record

ArticleAmerican journal of physiology. Renal physiology2021

Angiotensin type 2 receptor activation limits kidney injury during the early phase and induces Treg cells during the late phase of renal ischemia.

Riyasat Ali, Sanket Patel, Tahir Hussain

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Role of local angiotensin II signaling in bladder function.American journal of physiology. Renal physiology · 2024
    Review
  5. Renin-angiotensin system-mediated nitric oxide signaling in podocytes.American journal of physiology. Renal physiology · 2024
    Article
  6. Macrophage angiotensin ATAmerican journal of physiology. Renal physiology · 2023
    Article
  7. Article
  8. Article
  9. The Angiotensin ATPharmacological reviews · 2022
    Review
  10. Article
  11. Article
  12. Angiotensin ATFrontiers in immunology · 2022
    Article
  13. Article
  14. Review
  15. Targeting ATAmerican journal of physiology. Renal physiology · 2021
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Riyasat AliDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas.
Sanket PatelDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas.ORCID 0000-0003-1674-711X
Tahir HussainDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas.
University of Houston · US

Funding

Renal Angiotensin ll Receptor Function in ObesityR01DK061578 · NIDDK · UNIVERSITY OF HOUSTON · PI HUSSAIN, TAHIR · 2003 to 2020
$4.3M
Protective Arm of the Renin Angiotensin System in Obese KidneyR01DK117495 · NIDDK · UNIVERSITY OF HOUSTON · PI HUSSAIN, TAHIR · 2018 to 2021
$1.6M
HHS | National Institutes of Health (NIH) R01 DK61578NIDDK NIH HHS R01 DK061578NIDDK NIH HHS R01 DK117495
6 · The paper itself

Abstract

Kidney infiltrating immune cells such as monocytes, neutrophils, and T cells play critical roles in renal ischemia-reperfusion (IR) injury and repair. Recently, the angiotensin II type 2 receptor (AT

Indexed as

Acute Kidney InjuryAnimalsAnti-Inflammatory AgentsChemotaxis, LeukocyteCytokinesDisease Models, AnimalKidneyPhenotypeRatsRats, Sprague-DawleyReceptor, Angiotensin, Type 2Reperfusion InjurySignal TransductionSulfonamidesThiophenesTime FactorsAgtr2 protein, ratAnti-Inflammatory AgentsCytokinesN-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-isobutylthiophene-2-sulfonamideReceptor, Angiotensin, Type 2SulfonamidesThiophenesangiotensin II type 2 receptorC21FoxP3interleukin-10ischemia-reperfusion injury

Identifiers

PMID33719572
PMCPMC8424555
OpenAlexW3137436996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.