ReviewStroke2021
A Primary Care Agenda for Brain Health: A Scientific Statement From the American Heart Association.
Review in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07547319 (Clinical and Neurophysiological Effects of Accelerated rTMS on Cognitive Function), which is not on this map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical and Neurophysiological Effects of Accelerated rTMS on Cognitive Function: A Prospective Pilot Study
Who cites it
55 citing papers in PubMed.
- Differences in Cognitive Aging Assessments Associated With Retest Effects.JAMA network open · 2026Trial
- Trial
- Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial.Lancet (London, England) · 2023Trial
- Sleep Quality, Metabolic Function, Physical Activity, and Neurocognition Among Individuals with Resistant Hypertension.Journal of Alzheimer's disease : JAD · 2023Trial
- The path to treating multiple-etiology dementia: Combining vascular risk control and disease-modifying neurodegenerative therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Impaired Intracranial Compliance: A New Hypertension-Mediated Brain Organ Damage?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- LifeZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Review
- Article
- Review
- Rates, Risks, and Routes to Reduce Vascular Dementia: A UK-Wide Multicentre Prospective Observational Cohort Study of Cognition after Stroke - Baseline Data and Statistical Analysis Plan (ISRCTN18274006).Cerebrovascular diseases extra · 2026Observational
- Evaluation of perception towards brain health in Nigeria: Results from a nationwide awareness survey.Journal of public health in Africa · 2026Article
- Implementing brain health strategies in primary care: methods and baseline findings from the BHAM registry.Archives of public health = Archives belges de sante publique · 2025Article
- Importance of radiation-related cognitive decline in older adults who receive cranial radiation.Expert review of anticancer therapy · 2025Review
- U.S. public perceptions on whether risk of dementia and stroke can be modified through maintaining or changing lifestyle.BMC public health · 2025Article
- Relationship between sedentary time and cognitive decline in hypertensive patients-mediating role of the weight-adjusted waist circumference index.Scientific reports · 2025Article
- Obesity, Hypertension and Brain Health.Current hypertension reports · 2025Review
- Predicting White Matter Hyperintensity: Leveraging Portable MRI for Accessible Brain Health Screening.AJNR. American journal of neuroradiology · 2025Article
- Assocation Between a Brain Care Score Derived from Participant Responses and Incident Stroke from the COSMOS Study.American journal of lifestyle medicine · 2025Article
- Association of visual and hearing impairments with all-cause mortality in older adults in China.BMC geriatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
A healthy brain is critical for living a longer and fuller life. The projected aging of the population, however, raises new challenges in maintaining quality of life. As we age, there is increasing compromise of neuronal activity that affects functions such as cognition, also making the brain vulnerable to disease. Once pathology-induced decline begins, few therapeutic options are available. Prevention is therefore paramount, and primary care can play a critical role. The purpose of this American Heart Association scientific statement is to provide an up-to-date summary for primary care providers in the assessment and modification of risk factors at the individual level that maintain brain health and prevent cognitive impairment. Building on the 2017 American Heart Association/American Stroke Association presidential advisory on defining brain health that included "Life's Simple 7," we describe here modifiable risk factors for cognitive decline, including depression, hypertension, physical inactivity, diabetes, obesity, hyperlipidemia, poor diet, smoking, social isolation, excessive alcohol use, sleep disorders, and hearing loss. These risk factors include behaviors, conditions, and lifestyles that can emerge before adulthood and can be routinely identified and managed by primary care clinicians.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.