Evidence map›Paper›PMID 33719157›Full record

ArticleEMBO reports2021

Carbonic anhydrase seven bundles filamentous actin and regulates dendritic spine morphology and density.

Enni Bertling, Peter Blaesse, Patricia Seja, Elena Kremneva, Gergana Gateva, Mari A Virtanen, Milla Summanen, Inkeri Spoljaric, Pavel Uvarov, Michael Blaesse and 5 more

Open access · greenAbstract read
In one paragraph

Article in EMBO reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Developmental regulation of intestinalbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 3 countries.

Enni BertlingNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Peter BlaesseInstitute of Physiology I, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Patricia SejaNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5016-9961
Elena KremnevaInstitute of Biotechnology, Helsinki, Finland.
Gergana GatevaInstitute of Biotechnology, Helsinki, Finland.
Mari A VirtanenNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Milla SummanenNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Inkeri SpoljaricNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Pavel UvarovNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Michael BlaesseDornach-Aschheim, Germany.
Ville O PaavilainenInstitute of Biotechnology, Helsinki, Finland.ORCID 0000-0002-3160-7767
Laszlo VutskitsDepartment of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Kai KailaNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0668-5955
Pirta HotulainenNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0764-8582
Eva RuusuvuoriNeuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5493-1108
University of Helsinki · FIUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular pH is a potent modulator of neuronal functions. By catalyzing (de)hydration of CO

Indexed as

ActinsCarbonic AnhydrasesActin CytoskeletonDendritic SpinesHippocampusNeuronsActinsCarbonic Anhydrasesactin cytoskeletoncarbonic anhydrasedendritic spinesintracellular pHmultifunctional protein

Identifiers

PMID33719157
PMCPMC8025036
OpenAlexW3138607495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.