Evidence map›Paper›PMID 33718895›Full record

ArticleBrain, behavior, & immunity - health2020

Anhedonia and Increased Evoked Immune Response.

Anastacia Y Kudinova, Anny Gano, Kiera M James, Christian Lawlor, Terrence Deak, Brandon E Gibb

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Neuroinflammation in the Amygdala Is Associated With Recent Depressive Symptoms.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anastacia Y KudinovaBinghamton University (SUNY).
Anny GanoBinghamton University (SUNY).
Kiera M JamesBinghamton University (SUNY).
Christian LawlorBinghamton University (SUNY).
Terrence DeakBinghamton University (SUNY).
Brandon E GibbBinghamton University (SUNY).
Binghamton University · US

Funding

Social Anxiety, Stress and Ethanol Sensitivity in Adolescence and AdulthoodP50AA017823 · NIAAA · UPSTATE MEDICAL UNIVERSITY · PI Marvin Rafael Diaz · 2009 to 2026
$30.5M
RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Supplement to MH098060, “Children’s Attentional Biases: A Key Component of Negative Valence Systems.”R01MH098060 · NIMH · STATE UNIVERSITY OF NY,BINGHAMTON · PI GIBB, BRANDON E · 2012 to 2015
$3.1M
Neuroinflammation and social behavior across the lifespanR01AG043467 · NIA · STATE UNIVERSITY OF NY,BINGHAMTON · PI DEAK, TERRENCE · 2014 to 2018
$2.3M
Neural Mechanisms Underlying Self-Critical Rumination and Self-Reassurance and Suicidal Thoughts and Behavior in YouthK23MH122587 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI KUDINOVA, ANASTACIA Y. · 2020 to 2024
$1.0M
NIAAA NIH HHS P50 AA017823NIA NIH HHS R01 AG043467NIMH NIH HHS K23 MH122587NIMH NIH HHS R01 MH098060NIMH NIH HHS T32 MH019927
6 · The paper itself

Abstract

There is a growing body of evidence supporting the association between immune processes and psychopathology, including major depressive disorder (MDD). However, lack of diagnostic specificity has given rise to a search for specific symptom types, as opposed to more heterogeneous categorical diagnoses, linked to increased inflammation. One such symptom could be anhedonia, which is not only a key feature of MDD, but also a pervasive and persistent transdiagnostic symptom. To evaluate the specific role of anhedonia as well as categorical MDD diagnoses, we examined endotoxin-evoked immune responses

Indexed as

Anhedoniacytokinesinflammationmajor depressive disorderstimulated immune response

Identifiers

PMID33718895
PMCPMC7954217
OpenAlexW3033056228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.