ArticleMayo Clinic proceedings. Innovations, quality & outcomes2021
Reducing Blood Loss by Changing to Small Volume Tubes for Laboratory Testing.
Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Practical Anemia Bundle and Hemoglobin Recovery in Critical Illness: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Advances in the understanding and management of hospital-acquired anemia.Current opinion in anaesthesiology · 2026Review
- Patient blood management in general intensive care patients.Intensive care medicine · 2026Review
- Green CKD care: 10 tips to make nephrology outpatient clinics more environmentally sustainable.Clinical kidney journal · 2026Review
- Best practices for iatrogenic anaemia prevention in the intensive care unit: Blood-sparing techniques.Nursing in critical care · 2025Review
- Validation of low-volume blood collection tubes for routine hematologic testing.Journal of medical biochemistry · 2024Article
- Exploring the Impact of Blood Draws on the Intraocular Pressure of Older Adults: A Focus on Physiological Responses.Journal of clinical medicine · 2024Article
- Interventions to improve appropriateness of laboratory testing in the intensive care unit: a narrative review.Annals of intensive care · 2024Review
- Risk Factors Analysis for Hemoglobin Decline Caused by Diagnostic Blood Collection in Respiratory Department in North China: A Case-Control Study.International journal of general medicine · 2023Article
- Practical Anemia Bundle for Sustained Blood Recovery (PABST-BR) in critical illness: a protocol for a randomised controlled trial.BMJ open · 2022Article
- Avoidable Blood Loss in Critical Care and Patient Blood Management: Scoping Review of Diagnostic Blood Loss.Journal of clinical medicine · 2022Article
- Iatrogenic blood loss in critical care: A prospective observational study conducted at Universitas Academic Hospital in the Free State Province, South Africa.The Southern African journal of critical care : the official journal of the Critical Care Society · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo reduce diagnostic blood loss by using small volume tubes for routine laboratory testing throughout the hospital, as blood loss from laboratory testing can be substantial for patients and may lead to hospital-acquired anemia. PATIENTS AND
methodsDiagnostic blood loss was evaluated in hospitalized patients between April 1, 2017, and June 1, 2018. The preintervention, during intervention, and postintervention mean diagnostic blood loss per hospitalized patient was compared across the floors and for each type of tube for hematology, basic metabolic panel, and coagulation tests. Mean hemoglobin levels, blood transfusions per hospitalized patient, and percent redraws were also compared.
resultsThe total volume of blood drawn for all the 3 tests decreased across each implementation phase; however, only patients admitted to the transplant and critical care (T/CC) units had increased hemoglobin levels. In addition, there was a significant reduction in transfusions across implementation phases. The incidence risk ratio for transfusion reduced even more in patients admitted to the T/CC units. Finally, there was no significant difference in the overall percent redraws across all the units.
conclusionThe use of small volume tubes in exchange for standard sized tubes markedly decreased diagnostic blood loss by 25.7% in all the units and 22.9% in the T/CC units. Also, the number of transfusions decreased across units, with the greatest decrease in the T/CC units. An increase in mean hemoglobin levels was observed specifically in patients admitted to the T/CC units, with no corresponding change in percent redraws across all the units.
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