Evidence map›Paper›PMID 33718749›Full record

ArticlePediatric quality & safety

Decreasing Inappropriate Use of Antireflux Medications by Standardizing Gastroesophageal Reflux Disease Management in NICU.

Fauzia M Shakeel, Jacquelyn Crews, Preceous Jensen, Andrea Ritchey, Megan Allen, Jazmine Mateus, Joana Machry

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric quality & safety. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fauzia M ShakeelDepartment of Neonatology, Maternal Fetal and Neonatal Institute; Johns Hopkins All Children's Hospital St. Petersburg, Fla.
Jacquelyn CrewsDepartment of Pediatrics. Johns Hopkins All Children's Hospital, St. Petersburg, Fla.
Preceous JensenDepartment of Neonatology, Maternal Fetal and Neonatal Institute; Johns Hopkins All Children's Hospital St. Petersburg, Fla.
Andrea RitcheyDepartment of Neonatology, Maternal Fetal and Neonatal Institute; Johns Hopkins All Children's Hospital St. Petersburg, Fla.
Megan AllenDivision of Pharmacy and Therapeutics, Johns Hopkins All Children's Hospital, St. Petersburg, Fla.
Jazmine MateusDepartment of Health Informatics, Johns Hopkins Children's Hospital, St. Petersburg, Fla.
Joana MachryDepartment of Neonatology, Maternal Fetal and Neonatal Institute; Johns Hopkins All Children's Hospital St. Petersburg, Fla.
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroesophageal reflux (GER) is a functional self-limiting condition in neonates. When pathologic, it is called GER disease (GERD). There are wide variations in the management of signs, symptoms, and complications associated with GERD in the neonatal intensive care unit (NICU). Evidence does not support an empiric trial of GERD medications as a diagnostic tool or therapy in premature infants.

methodsA multidisciplinary team developed evidence-based clinical practice guidelines (CPG) for GERD management. Process improvement included developing a GERD management algorithm, electronic order sets, and education for all providers. Multiple plan-do-study-act cycles done.

resultsImplementation of standardized GERD management guideline, decreased the overall use of antireflux medications from baseline, 15.1%-6.8% [χ

conclusionStandardizing clinical management leads to best practices for GERD management with appropriate diagnostic testing, eliminating incorrect medication dosing, and improved patient safety with value-based outcomes.

Identifiers

PMID33718749
PMCPMC7952116
OpenAlexW2886328910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.