Evidence map›Paper›PMID 33718693›Full record

ArticleCurrent opinion in physiology2021

Converging integration between ascending proprioceptive inputs and the corticospinal tract motor circuit underlying skilled movement control.

John Kalambogias, Yutaka Yoshida

Abstract read
In one paragraph

Article in Current opinion in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Observational
  3. Review
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John KalambogiasBurke Neurological Institute, White Plains, New York 10605.
Yutaka YoshidaBurke Neurological Institute, White Plains, New York 10605.

Funding

Synapse elimination in the central nervous systemR01NS093002 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI YOSHIDA, YUTAKA · 2015 to 2024
$4.6M
A novel combinatorial approach to restore motor function after spinal cord injuryR01NS100772 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI YOSHIDA, YUTAKA · 2017 to 2021
$1.9M
Regulation of Sensory-Motor Connectivity by Semaphorin-Plexin SignalingR01NS065048 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI YOSHIDA, YUTAKA · 2009 to 2013
$1.6M
NINDS NIH HHS R01 NS065048NINDS NIH HHS R01 NS093002NINDS NIH HHS R01 NS100772
6 · The paper itself

Abstract

Converging interactions between ascending proprioceptive afferents and descending corticospinal tract projections are critical in the modulation and coordination of skilled motor behaviors. Fundamental to these processes are the functional inputs and the mechanisms of integration in the brain and spinal cord between proprioceptive and corticospinal tract information. In this review, we first highlight key connections between corticospinal tract motor circuit and spinal interneurons that receive proprioceptive inputs. We will also address corticospinal tract access to the presynaptic inhibitory system in the spinal cord and its role in modulating proprioceptive stimuli. Lastly, we will focus on the corticospinal neuron influences on the dorsal column nuclei complex, an integration hub for processing ascending somatosensory information.

Indexed as

corticospinal neuronsmotor cortexproprioceptive sensory neuronsspinal cord

Identifiers

PMID33718693
PMCPMC7949357

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.