Evidence map›Paper›PMID 33718555›Full record

ArticleArthroplasty today2021

Management of Periprosthetic Joint Infection and Extensor Mechanism Disruption With Modular Knee Fusion: Clinical and Biomechanical Outcomes.

Wesley H Mayes, Anna C Severin, Erin M Mannen, Paul K Edwards, C Lowry Barnes, Jeffrey B Stambough, Simon C Mears

Open access · goldAbstract read
In one paragraph

Article in Arthroplasty today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wesley H MayesDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Anna C SeverinDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Erin M MannenDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Paul K EdwardsDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
C Lowry BarnesDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Jeffrey B StamboughDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Simon C MearsDepartment of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
University of Arkansas for Medical Sciences · US

Funding

Understanding the Negative Prognostic Impact of Intraosseous Focal Lesions in Multiple MyelomaP20GM125503 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Sanja Novak · 2018 to 2026
$23.0M
NIGMS NIH HHS P20 GM125503
6 · The paper itself

Abstract

backgroundExtensor mechanism disruption (EMD) combined with periprosthetic joint infection (PJI) after total knee arthroplasty are life-changing complications. The literature suggests many eventually receive above-knee amputation and lose ambulatory function. An alternative is modular knee fusion (KF), but little is known about its outcomes and biomechanical function. We report early term results on a case series of patients.

methodsA retrospective review was conducted of patients who underwent 2-stage reconstruction with modular KF for combined EMD and PJI. Patient-reported outcomes at 1 year after arthrodesis and complications of surgery were recorded. Biomechanical analysis was conducted on 6 patients >1 year after surgery to measure gait speed and balance.

resultsFifteen patients received a modular KF. At the most recent follow-up visit (average 25.7 months), 12 patients had their modular KFs in place and were ambulatory while 2 had died. Six patients used a walker; 4, a cane; and 2, unassisted. Gait analysis of 6 of these patients showed variation in patterns and speed. Balance was better than historical controls treated with above-knee amputation. Average Knee Injury and Osteoarthritis Outcome Score Junior was 76 ± 11.

conclusionModular KF for EMD and PJI can result in successful outcomes in terms of preventing additional operations and maintaining ambulation. While speed is variable, physical testing shows this method for limb salvage may allow patients to ambulate with a gait aid although further studies are needed to evaluate midterm and long-term results.

Indexed as

Extensor mechanism failureGait analysisKnee fusionProsthetic joint infection

Identifiers

PMID33718555
PMCPMC7921710
OpenAlexW3133971566

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.