ArticleCurrent opinion in behavioral sciences2021
Neural circuits for inference-based decision-making.
Article in Current opinion in behavioral sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Group membership and stereotype content jointly affect neural processing during resource allocation decisions.Scientific reports · 2025Article
- Distinct contributions of anterior and posterior orbitofrontal cortex to outcome-guided behavior.bioRxiv : the preprint server for biology · 2025Article
- Article
- Hippocampal and orbitofrontal neurons contribute to complementary aspects of associative structure.Nature communications · 2024Article
- Midbrain signaling of identity prediction errors depends on orbitofrontal cortex networks.Nature communications · 2024Article
- Lateral orbitofrontal cortex integrates predictive information across multiple cues to guide behavior.Current biology : CB · 2023Article
- Computationally Informed Interventions for Targeting Compulsive Behaviors.Biological psychiatry · 2023Review
- Article
- Reward Uncertainty and Expected Value Enhance Generalization of Episodic Memory.International journal of environmental research and public health · 2022Article
- The mediodorsal thalamus supports adaptive responding based on stimulus-outcome associations.Current research in neurobiology · 2022Article
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2 authors.
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Abstract
In novel situations, where direct experience is lacking or outdated, humans must rely on mental simulations to predict future outcomes. This review discusses recent work on the neural circuits that support such inference-based behavior. We focus on two specific examples: 1) using knowledge about the associative structure of the world to infer outcomes when direct experience is lacking; 2) inferring the current value of options when the desirability of the associated outcome has changed since the original learning experience. These two examples can be studied in the sensory preconditioning and devaluation tasks, respectively. We review results from studies in animals and humans suggesting that the orbitofrontal cortex (OFC), together with the hippocampus and amygdala, is necessary for inference in both of these tasks. Together, these findings suggest that the OFC is a critical hub in the brain network that supports inference-based decision-making.
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