ArticleOrthopaedic journal of sports medicine2021
Relationship of Anterior Cruciate Ligament Volume and T2* Relaxation Time to Anterior Knee Laxity.
Article in Orthopaedic journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Relationship Between Quantitative MRI UTE T2* of ACL Autografts and BMI-Normalized Knee Laxity Within the First Year After ACL Reconstruction.The American journal of sports medicine · 2025Article
- Sex Hormone Profiles and ACL Injury - It's Time for Study Designs to Match the Complexity of the Problem.Sports health · 2025Article
- Multiscale correlations between joint and tissue-specific biomechanics and anatomy in postmortem ovine stifles.Scientific reports · 2025Article
- Quantitative assessment of anterior talofibular ligament quality in chronic lateral ankle instability using magnetic resonance imaging T2* value.Skeletal radiology · 2024Article
- Sex-Specific Changes in Physical Risk Factors for Anterior Cruciate Ligament Injury by Chronological Age and Stages of Growth and Maturation From 8 to 18 Years of Age.Journal of athletic training · 2022Article
- ACL Research Retreat IX Summary Statement: The Pediatric Athlete, March 17-19, 2022; High Point, North Carolina.Journal of athletic training · 2022Article
- Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh anterior knee laxity (AKL) has been prospectively identified as a risk factor for anterior cruciate ligament (ACL) injuries. Given that ACL morphometry and structural composition have the potential to influence ligamentous strength, understanding how these factors are associated with greater AKL is warranted. HYPOTHESIS: Smaller ACL volumes combined with longer T2* relaxation times would collectively predict greater AKL. STUDY
designCross-sectional study; Level of evidence, 3.
methodsCollege-aged active male (n = 20) and female (n = 30) participants underwent magnetic resonance imaging (MRI) and AKL testing. T2-weighted MRI scans were used to assess ACL volumes, and T2* relaxation times were used to assess ACL structural composition. AKL was measured via a commercial knee arthrometer. Forward stepwise linear regression with sex and weight (first step; suppressor variables) as well as ACL volume and T2* relaxation time (second step; independent variables) was used to predict AKL (dependent variable).
resultsAfter initially adjusting for sex and weight (
conclusionAKL was largely predicted by ACL volume and to a lesser extent by T2* relaxation time (and not a person's sex and weight). These findings enhance our understanding of how AKL may be associated with a structurally weaker ACL. The current study presents initial evidence that AKL is a cost-effective and clinically accessible measure that shows us something about the structural composition of the ACL. As AKL has been consistently shown to be a risk factor for ACL injuries, work should be done to continue to investigate what AKL may tell a clinician about the structure and composition of the ACL.
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