Evidence map›Paper›PMID 33718452›Full record

ArticleFrontiers in cardiovascular medicine2021

Single-Cell Transcriptome Analysis Decipher New Potential Regulation Mechanism of ACE2 and NPs Signaling Among Heart Failure Patients Infected With SARS-CoV-2.

Mengqiu Ma, Yanhua Xu, Yang Su, Sang-Bing Ong, Xingdong Hu, Min Chai, Maojun Zhao, Hong Li, Xiaojuan Fan, Yingjie Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high-fat diet.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  4. Interferons and interferon-related pathways in heart disease.Frontiers in cardiovascular medicine · 2024
    Review
  5. Review
  6. Article
  7. COVID-19 and myocarditis: a review of literature.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Review
  8. Therapeutic prospects of ceRNAs in COVID-19.Frontiers in cellular and infection microbiology · 2022
    Review
  9. Observational
  10. Models for COVID-19 Early Cardiac Pathology Following SARS-CoV-2 Infection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  11. Article
  12. SARS-CoV-2: is there neuroinvasion?Fluids and barriers of the CNS · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Mengqiu MaDepartment of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yanhua XuDepartment of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yang SuDepartment of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Sang-Bing OngCentre for Cardiovascular Genomics and Medicine (CCGM), Lui Che Woo Institute of Innovative Medicine, Chinese University of Hong Kong (CUHK), Hong Kong, China.
Xingdong HuDepartment of Critical Care Medicine, The Third people's Hospital of Guizhou Province, Guiyang, China.
Min ChaiDepartment of Critical Care Medicine, Ezhou Central Hospital, Ezhou, China.
Maojun ZhaoEmergency Department, The First People's Hospital of Guiyang, Guiyang, China.
Hong LiImmunity, Inflammation & Disease Laboratory, The National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, United States.
Xiaojuan FanKey Laboratory of Environment and Genes Related to Diseases, Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yingjie ChenDepartment of Physiology & Biophysics, University of Mississippi Medical Center, Jackson, MS, United States.
Dachun XuDepartment of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaojiang XuKelly Government Solutions, Rockville, MD, United States.
Tongji University · CNEzhou Central Hospital · CNFirst Affiliated Hospital of Xiamen University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNGuizhou Provincial People's Hospital · CNJackson Memorial Hospital · USKelly Services (United States) · USNational Institute of Environmental Health Sciences · USShanghai Tenth People's Hospital · CNThe First People's Hospital of Guiyang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

angiotensin converting enzyme 2COVID-19heart failureSARS-CoV-2single-cell RNA sequencing

Identifiers

PMID33718452
PMCPMC7952310
OpenAlexW3134629836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.