Evidence map›Paper›PMID 33718361›Full record

ReviewFrontiers in cell and developmental biology2021

Advances in the Relationship Between Regulator of Ribosome Synthesis 1 (RRS1) and Diseases.

Yanan Hua, Jinlian Song, Cuixiu Peng, Runze Wang, Zhongliang Ma, Jinyu Zhang, Zheng Zhang, Ning Li, Lin Hou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. World journal of gastrointestinal oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yanan HuaDepartment of Neurobiology, Basic Medical College, Qingdao University, Qingdao, China.
Jinlian SongDepartment of Laboratory, Women and Children's Hospital of Qingdao, Qingdao, China.
Cuixiu PengDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Runze WangDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Zhongliang MaDepartment of Breast Surgery, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Jinyu ZhangDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Zheng ZhangDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Ning LiDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Lin HouDepartment of Biochemistry and Molecular Biology, Basic Medical College, Qingdao University, Qingdao, China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A regulator of ribosome synthesis 1 (RRS1) was discovered in yeast and is mainly localized in the nucleolus and endoplasmic reticulum. It regulates ribosomal protein, RNA biosynthesis, and protein secretion and is closely involved in cellular senescence, cell cycle regulation, transcription, translation, oncogenic transformation etc., Mutations in the RRS1 gene are associated with the occurrence and development of Huntington's disease and cancer, and overexpression of RRS1 promotes tumor growth and metastasis. In this review, the structure, function, and mechanisms of RRS1 in various diseases are discussed.

Indexed as

cancerdiseasemolecular mechanismribosomeRRS1

Identifiers

PMID33718361
PMCPMC7947238
OpenAlexW3132002386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.