Evidence map›Paper›PMID 33718350›Full record

ArticleFrontiers in cell and developmental biology2021

Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer.

John Greene, Anne-Marie Baird, Marvin Lim, Joshua Flynn, Ciara McNevin, Lauren Brady, Orla Sheils, Steven G Gray, Raymond McDermott, Stephen P Finn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

John GreeneDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Anne-Marie BairdSchool of Medicine, Trinity Translational Medicine Institute, Trinity College, Dublin, Ireland.
Marvin LimDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Joshua FlynnSchool of Medicine, Trinity Translational Medicine Institute, Trinity College, Dublin, Ireland.
Ciara McNevinDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Lauren BradyDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Orla SheilsDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Steven G GraySchool of Medicine, Trinity Translational Medicine Institute, Trinity College, Dublin, Ireland.
Raymond McDermottDepartment of Medical Oncology, Tallaght University Hospital, Dublin, Ireland.
Stephen P FinnDepartment of Histopathology and Morbid Anatomy, School of Medicine, Trinity College, Dublin, Ireland.
Trinity College Dublin · IESt. James's Hospital · IETallaght University Hospital · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs), a recently discovered non-coding RNA, have a number of functions including the regulation of miRNA expression. They have been detected in a number of malignancies including prostate cancer (PCa). The differential expression pattern of circRNAs associated with PCa and androgen receptor (AR) status was investigated in this study. circRNA profiling was performed using a high throughout microarray assay on a panel of prostate cell lines, which consisted of normal, benign, and malignant cells (

Indexed as

androgen signalingbiomarkerscircRNAnon-coding RNAprostate cancer

Identifiers

PMID33718350
PMCPMC7946979
OpenAlexW3129774635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.