Evidence map›Paper›PMID 33718344›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Tropoelastin and Elastin Assembly.

Jazmin Ozsvar, Chengeng Yang, Stuart A Cain, Clair Baldock, Anna Tarakanova, Anthony S Weiss

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 133 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Observational
  5. RiboScreenBiomedicines · 2026
    Review
  6. AI-validated fusion proteins for local inhibition of interleukin-17A.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  7. Glycocalyx and basal lamina in neurological disorders.Matrix biology : journal of the International Society for Matrix Biology · 2026
    Review
  8. Functions of prolyl hydroxylation in elastin.The Journal of biological chemistry · 2026
    Article
  9. Extracellular stiffness regulates cell fate determination and drives the emergence of evolutionary novelty in the teleost heart.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Bio-Inspired and Protein-Based Elastomeric Materials.Polymer science & technology (Washington, D.C.) · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Jazmin OzsvarCharles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Chengeng YangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT, United States.
Stuart A CainWellcome Trust Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.
Clair BaldockWellcome Trust Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.
Anna TarakanovaDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT, United States.
Anthony S WeissCharles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
University of Connecticut · USUniversity of Sydney · AUManchester Academic Health Science Centre · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin's structure and function.

Indexed as

assemblycomputational modelingelastic fiberselastintropoelastin

Identifiers

PMID33718344
PMCPMC7947355
OpenAlexW3128428045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.