Evidence map›Paper›PMID 33718278›Full record

ArticleFrontiers in cellular and infection microbiology2021

Genome-Wide Scans for Ghanaian

Shan-Mei Shi, Tian-Qi Shi, Shen-Bo Chen, Yan-Bing Cui, Kokouvi Kassegne, Moses Okpeku, Jun-Hu Chen, Hai-Mo Shen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Shan-Mei ShiNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Tian-Qi ShiNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Shen-Bo ChenNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Yan-Bing CuiNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Kokouvi KassegneNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Moses OkpekuDiscipline of Genetics, School of Life Science, University of Kwazulu-Natal, Durban, South Africa.
Jun-Hu ChenNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
Hai-Mo ShenNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health, National Centre for International Research on Tropical Diseases, WHO Collaborating Center for Tropical Diseases, Shanghai, China.
National Institute for Parasitic Diseases · CNUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initial malarial infection mostly causes symptomatic illness in humans. Infection that is not fatal induces complete protection from severe illness and death, and thus complete protection from severe illness or death is granted with sufficient exposure. However, malaria parasite immunity necessitates constant exposure. Therefore, it is important to evaluate lowered immunity and recurrent susceptibility to symptomatic disease in lower transmission areas. We aimed to investigate selection pressure based on transmission levels, antimalarial drug use, and environmental factors. We whole genome sequenced (WGS)

Indexed as

AntimalarialsMalaria, FalciparumChinaGhanaHumansPlasmodium falciparumAntimalarialsacquired immunityGhanaimported malariaPlasmodium falciparumpositive selectionvariant surface antigen

Identifiers

PMID33718278
PMCPMC7947188
OpenAlexW3131724713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.