Evidence map›Paper›PMID 33718274›Full record

ArticleFrontiers in cellular and infection microbiology2021

Proto-Oncogenes and Cell Cycle Gene Expression in Normal and Neoplastic Oral Epithelial Cells Stimulated With Soluble Factors From Single and Dual Biofilms of

María Isabel Amaya Arbeláez, Ana Carolina Alves de Paula E Silva, Geovana Navegante, Valeria Valente, Paula Aboud Barbugli, Carlos Eduardo Vergani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Worldwide trend in research onFrontiers in microbiology · 2024
    Pooled it
  2. Article
  3. Article
  4. [Defect modification of calcium silicate and its application in oral bacteriostasis and tooth remineralization].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. A customizable and defined medium supporting culturing ofApplied and environmental microbiology · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Cross-kingdom interaction betweenFrontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

María Isabel Amaya ArbeláezLaboratory of Applied Microbiology, Faculty of Dentistry, Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp), Araraquara, Brazil.
Ana Carolina Alves de Paula E SilvaLaboratory of Applied Microbiology, Faculty of Dentistry, Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp), Araraquara, Brazil.
Geovana NaveganteLaboratory of Molecular and Cell Biology, School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University (Unesp), Araraquara, Brazil.
Valeria ValenteLaboratory of Molecular and Cell Biology, School of Pharmaceutical Sciences, Department of Clinical Analysis, São Paulo State University (Unesp), Araraquara, Brazil.
Paula Aboud BarbugliLaboratory of Applied Microbiology, Faculty of Dentistry, Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp), Araraquara, Brazil.
Carlos Eduardo VerganiLaboratory of Applied Microbiology, Faculty of Dentistry, Department of Dental Materials and Prosthodontics, São Paulo State University (Unesp), Araraquara, Brazil.
Centro Universitário de Araraquara · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed at analyzing proto-oncogenic signaling pathway activation in normal oral keratinocytes (NOK-si) and neoplastic cell lines (SCC 25 and Detroit 562) stimulated with metabolites (soluble factors) from single and dual biofilms of

Indexed as

Candida albicansStaphylococcus aureusBiofilmsEpithelial CellsGenes, cdcProto-OncogenesbiofilmsCandida albicansgene expressionmetabolitesoral cancerStaphylococcus aureus

Identifiers

PMID33718274
PMCPMC7947338
OpenAlexW3131603248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.