ArticleFrontiers in oncology2021
Case Report: Adjuvant Radiotherapy Can Be an Effective Treatment for Intimal Sarcoma of the Heart.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Right atrial intimal sarcoma with liver metastasis: A case report and literature review.Cancer pathogenesis and therapy · 2026Article
- Case Report: Adjuvant radiation therapy for cardiac intimal sarcoma with long-term disease control.Frontiers in oncology · 2026Article
- Primary Cardiac Sarcomas: Clinical Characteristics, Management, and Outcomes at a Spanish National Reference Center.Cancers · 2025Article
- Case report: Cardiac myxoid fibrosarcoma: a report of two cases.Frontiers in oncology · 2025Article
- A Comprehensive Insight Into Primary Intimal Sarcoma of the Pulmonary Artery; From Diagnosis to Management: A Case Report and Review of the Literature.Clinical case reports · 2024Article
- Stepwise Use of Multimodality Imaging in a Rare Cardiac Intimal Sarcoma.CASE (Philadelphia, Pa.) · 2023Article
- Postoperative radiotherapy for high-grade primary cardiac spindle cell sarcoma: a rare entity.BMJ case reports · 2023Article
- Anlotinib plus Chemotherapy for the Treatment of Refractory Primary Cardiac Intimal Sarcoma: A Case Report.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intimal sarcoma of the heart is a sporadic disease, which involves symptoms of cardiac insufficiency due to a fast-growing intraluminal mass. Tumor resection is the first-line treatment, although its location precludes excision with wide uninvolved margins. Despite the aggressiveness of this neoplasm and a high risk of recurrence even after removal by microscopically radical surgery, no standard adjuvant therapy has been established. Chemotherapy is used either as an adjuvant treatment or in cases of advanced disease. In contrast, the use of radiotherapy is rare and usually considered in a palliative setting because the risk of radiation-induced heart disease after high-dose radiotherapy to the heart is significant. Herein, we present the cases of two patients, both diagnosed with cardiac intimal sarcoma, who received irradiation after tumor resection. In both cases, radiotherapy was effective, providing long-lasting local disease control. We regularly monitored cardiac function in both patients to assess the impact of radiotherapy on tumor-free heart structures. The excellent local control of the disease with only mild long-term cardiac dysfunction in both patients suggests that radiotherapy can be a useful treatment modality in this indication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.