SynthesisFrontiers in oncology2020
A Meta-Analysis of Risk Factors for Transient and Permanent Hypocalcemia After Total Thyroidectomy.
Synthesis in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- The outcomes of parathyroid gland autotransplantation during thyroid surgery: a systematic review, meta-analysis and trial sequential analysis.Endocrine · 2025Pooled it
- No Change in Complications Following Thyroidectomy Despite Increase in Thyroid Cancer Surgeries: A Meta-Regression Analysis.Yonsei medical journal · 2024Pooled it
- The effect of reminder mobile application use on medication adherence after total thyroidectomy: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Modeling the Relationship of Age With Hypocalcemia Following Total Thyroidectomy: A NSQIP Analysis.Laryngoscope investigative otolaryngology · 2026Article
- Indications and Complications of Total Thyroidectomy in the Management of Thyroid Diseases: A Five-Year Retrospective Study in a Greek Population.Acta medica academica · 2026Article
- Development and validation of an explainable web-based machine learning model for predicting early postoperative hypocalcemia in patients with differentiated thyroid cancer.Gland surgery · 2026Article
- Impact of intraoperative parathyroid identification and accidental removal on post-thyroidectomy hypocalcemia: a single-center 15-year experience.BMC surgery · 2026Article
- Early Detection of Transient Hypoparathyroidism After Total Thyroidectomy: A Single-Center Preliminary Study.Medicina (Kaunas, Lithuania) · 2026Article
- Artificial intelligence for predicting transient hypocalcemia after total thyroidectomy.Scientific reports · 2026Article
- Predicting Hypocalcemia and Identifying Supplementation Needs After Total Thyroidectomy: The Role of Perioperative PTH Measurements.Biomedicines · 2025Article
- Reversible heart failure secondary to hypocalcemia in a post-thyroidectomy patient: a rare case report.Annals of medicine and surgery (2012) · 2025Article
- Surgical Timing in Thyroid Cancer with Lateral Neck Metastases: Delayed Versus Contemporary Lateral Neck Dissection.Cancers · 2025Article
- Ionized calcium and PTH as predictors of hypoparathyroidism following total thyroidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Hypocalcemia After Thyroidectomy in Patients Taking Proton Pump Inhibitors.Laryngoscope investigative otolaryngology · 2025Article
- Predictive factors for permanent hypoparathyroidism following total thyroidectomy: A retrospective cohort study of 5,671 cases.Archives of endocrinology and metabolism · 2025Article
- Effect of Histamine-2 Receptor Antagonists on Hypocalcemia after Thyroidectomy: A Retrospective Cohort Study and Sensitivity Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Impact of thyroid volume on serum ionized calcium and PTH levels after total thyroidectomy.Sao Paulo medical journal = Revista paulista de medicina · 2025Observational
- Gasless versus gas-inflated transaxillary endoscopic thyroidectomy for papillary thyroid carcinoma: a cohort study on surgical outcomes and learning curves.Frontiers in endocrinology · 2025Article
- Preoperative serum indicators as predictors of postoperative hypoparathyroidism following thyroidectomy.Frontiers in endocrinology · 2025Article
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Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs hypocalcemia is the most common complication of total thyroidectomy, identifying its risk factors should guide prevention and management. The purpose of this study was to determine the risk factors for postthyroidectomy hypocalcemia.
methodsWe searched PubMed, Web of Science and EMBASE through January 31, 2019, and assessed study quality using the Newcastle-Ottawa Scale.
resultsFifty studies with 22,940 patients met the inclusion criteria, of which 24.92% (5716/22,940) had transient hypocalcemia and 1.96% (232/11,808) had permanent hypocalcemia. Significant (
conclusionImportant risk factors for transient and permanent hypocalcemia were identified. However, given the limited sample size and heterogeneity of this meta-analysis, further studies are required to confirm our preliminary findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.