Evidence map›Paper›PMID 33717995›Full record

ArticleToxicology reports2021

Long-term ecotoxicological effects of ciprofloxacin in combination with caffeine on the microalga

Vinicius Diniz, Gabriela Rath, Susanne Rath, Caio Rodrigues-Silva, José R Guimarães, Davi G F Cunha

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 43 citations in OpenAlex.

  1. A Multifunctional MoSACS omega · 2026
    Article
  2. Article
  3. The Potential Role of Ecotoxicological Data in National Essential Medicine Lists: A Cross-Sectional Analysis.International journal of environmental research and public health · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vinicius DinizDepartment of Infrastructure and Environment, School of Civil Engineering, Architecture and Urban Design, University of Campinas, Campinas, Brazil.
Gabriela RathInstitute of Chemistry, University of Campinas, Campinas, Brazil.
Susanne RathInstitute of Chemistry, University of Campinas, Campinas, Brazil.
Caio Rodrigues-SilvaInstitute of Chemistry, University of Campinas, Campinas, Brazil.
José R GuimarãesDepartment of Infrastructure and Environment, School of Civil Engineering, Architecture and Urban Design, University of Campinas, Campinas, Brazil.
Davi G F CunhaDepartment of Hydraulics and Sanitation, São Carlos School of Engineering, University of São Paulo, São Carlos, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciprofloxacin (CIP) is an antimicrobial "pseudo-persistent" in aquatic ecosystems. Once dispersed in the water compartments, it can also affect the microalgae. Thus, the evaluation of its long-term ecotoxicological effects is necessary. CIP interactions with other pharmaceuticals are not well known. In this study, we investigated the toxic effects of CIP alone and combined with caffeine (CAF), using the modified Gompertz model parameters and the chlorophyll-a production of the microalga

Indexed as

ChlorophyceaeCiprofloxacinEcotoxicological assaysEffect concentrationEndpointsExposure time

Identifiers

PMID33717995
PMCPMC7932887
OpenAlexW3132228110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.