ArticleJournal of clinical orthopaedics and trauma2021
Effect of heterotopic ossification after bryan-cervical disc arthroplasty on adjacent level range of motion: A finite element study.
Article in Journal of clinical orthopaedics and trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Long-Term Clinical and Radiographic Outcomes After Bryan Cervical Disk Arthroplasty: A Systematic Literature Review.Acta neurochirurgica. Supplement · 2023Pooled it
- Biomechanical evaluation on a new type of vertebral titanium porous mini-plate and mechanical comparison between cervical open-door laminoplasty and laminectomy: a finite element analysis.Frontiers in bioengineering and biotechnology · 2024Article
- Does the novel artificial cervical joint complex resolve the conflict between stability and mobility after anterior cervical surgery? a finite element study.Frontiers in bioengineering and biotechnology · 2024Article
- Machine learning for image analysis in the cervical spine: Systematic review of the available models and methods.Brain & spine · 2022Review
- Biomechanical Evaluation of Different Surgical Approaches for the Treatment of Adjacent Segment Diseases After Primary Anterior Cervical Discectomy and Fusion: A Finite Element Analysis.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuantitative bone re-modelling theories suggest that bones adapt to mechanical loading conditions. Follow-up studies have shown that total disc replacement (TDR) modifies stress patterns in the bones, leading to heterotopic ossification (HO). Although there are a few studies on HO using finite element models (FEM), its effect on the adjacent levels and change in range of motion (ROM) have not been adequately investigated. This study interfaces the HO using bone re-modelling algorithm with a finite element solution and investigates the subsequent changes in segmental ROM.
methodsA FEM of the human cervical spine (C3-C7) was developed for this study, with material properties obtained from literature. The motion of the segments in the sagittal, frontal and transverse planes under combined loading conditions of 1 Nm moment and 73.6 N compression were validated against experimental corridors. The natural disc between the C5-C6 segment was replaced with the Bryan artificial cervical disc, and changes in sagittal ROM were compared before and after HO. The process of HO was simulated using a bone remodelling algorithm using strain energy density (SED) as the mechanical stimuli. RESULTS AND
conclusionOur study demonstrates the feasibility of using SED calculations from the flexion-extension loading conditions for prediction of HO after ADR. The current findings suggest that the nature of trabecular stresses, and the subsequent rate and location of HO formation could differ based on the geometric design and nature of constraint for different artificial discs. The Bryan disc significantly reduced ROM at the implanted level in flexion. However, in extension, ROM increased at the implanted level and decreased slightly at the adjacent levels. After HO, ROM drastically reduced at the implanted level in both extension and flexion, and showed a minor increase in the adjacent levels, indicating that biomechanical behavior of high-grade HO is similar to a fused segment, thereby reducing the intended and initial motion preservation.
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