Evidence map›Paper›PMID 33717850›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Chiral Systems Made from DNA.

David Winogradoff, Pin-Yi Li, Himanshu Joshi, Lauren Quednau, Christopher Maffeo, Aleksei Aksimentiev

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Chirality Makes or Breaks Chemically Driven Self-Assembly.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Electroanalytical Quantification of DNA Chirality.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Vibrational circular dichroism unveils hidden clues.Light, science & applications · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David WinogradoffCenter for the Physics of Living Cells University of Illinois at Urbana-Champaign Urbana IL USA.
Pin-Yi LiDepartment of Physics University of Illinois at Urbana-Champaign Urbana IL USA.
Himanshu JoshiDepartment of Physics University of Illinois at Urbana-Champaign Urbana IL USA.
Lauren QuednauCenter for the Physics of Living Cells University of Illinois at Urbana-Champaign Urbana IL USA.
Christopher MaffeoCenter for the Physics of Living Cells University of Illinois at Urbana-Champaign Urbana IL USA.
Aleksei AksimentievCenter for the Physics of Living Cells University of Illinois at Urbana-Champaign Urbana IL USA.ORCID https://orcid.org/0000-0002-6042-8442

Funding

WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SCHULTEN, KLAUS · 2012 to 2021
$19.0M
Multi-resolution Approaches to Modeling the 3D Structure, Delivery, and Replication of Viral GenomesR01GM137015 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI AKSIMENTIEV, ALEKSEI · 2020 to 2023
$1.2M
NIGMS NIH HHS P41 GM104601NIGMS NIH HHS R01 GM137015
6 · The paper itself

Abstract

The very chemical structure of DNA that enables biological heredity and evolution has non-trivial implications for the self-organization of DNA molecules into larger assemblies and provides limitless opportunities for building functional nanostructures. This progress report discusses the natural organization of DNA into chiral structures and recent advances in creating synthetic chiral systems using DNA as a building material. How nucleic acid chirality naturally comes into play in a diverse array of situations is considered first, at length scales ranging from an individual nucleotide to entire chromosomes. Thereafter, chiral liquid crystal phases formed by dense DNA mixtures are discussed, including the ongoing efforts to understand their origins. The report then summarizes recent efforts directed toward building chiral structures, and other structures of complex topology, using the principle of DNA self-assembly. Discussed last are existing and proposed functional man-made nanostructures designed to either probe or harness DNA's chirality, from plasmonics and spintronics to biosensing.

Indexed as

DNA origamiliquid crystalsnanotechnologyplasmonicsself‐assembly

Identifiers

PMID33717850
PMCPMC7927625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.