Evidence map›Paper›PMID 33717505›Full record

ArticleCurrent health sciences journal

Biliary Stenting for Malignant Biliary Obstruction Secondary to Pancreatic Cancer.

Alexandru Constantinescu, Vasile Şandru, Madalina Ilie, Bogdan Silviu Ungureanu, Dan IonuŢ Gheonea, Tudorel Ciurea, Sergiu Marian Cazacu, Cristin-Constantin Vere, Gabriel Constantinescu

Open access · greenAbstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alexandru ConstantinescuPhD Student, University of Medicine and Pharmacy of Craiova, Romania.
Vasile ŞandruDepartment of Gastroenterology, Bucharest Emergency Clinic Hospital, Bucharest, Romania.
Madalina IlieDepartment of Gastroenterology, Bucharest Emergency Clinic Hospital, Bucharest, Romania.
Bogdan Silviu UngureanuDepartment of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania.
Dan IonuŢ GheoneaDepartment of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania.
Tudorel CiureaDepartment of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania.
Sergiu Marian CazacuDepartment of Gastroenterology, University of Medicine and Pharmacy of Craiova, Romania.
Cristin-Constantin VereDepartment of Gastroenterology, Bucharest Emergency Clinic Hospital, Bucharest, Romania.
Gabriel ConstantinescuDepartment of Gastroenterology, Bucharest Emergency Clinic Hospital, Bucharest, Romania.
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite progresses made in oncology, pancreatic adenocarcinoma has a grim prognosis and commonly presents with rapidly advancing jaundice which requires endoscopic treatment.

aimOur objective was to show the perspective of a high ERCP volume dedicated Center on endoscopic stenting for malignant biliary obstruction consecutive to pancreatic cancer.

methodsWe conducted a retrospective study, between October 2017 and October 2020, and enrolled hospitalized patients within the Gastroenterology Department of the Clinical Emergency Hospital Bucharest, diagnosed with pancreatic cancer with secondary malignant biliary obstruction which underwent ERCP stenting.

resultsWe identified 269 patients which were admitted in our Clinic with a pancreatic lesion on computed tomography or magnetic resonance imaging and underwent EUS-FNA. 115 patients with proven pancreatic malignancy were selected and underwent ERCP stenting. 69 received plastic stents and 46 metal biliary stents, with the stent chosen based on patient's characteristics and availability at the time of the procedure. Per total 234 stents were used for relief of the cholestasis syndrome. The number of ERCP procedures was higher in the plastic stents group with a median of 1,8 whereas the SEMS had 1,5 range of procedures. Procedures were successful in 54 patients following plastic stents and 33 that underwent SEMS. At 30 days, overall mortality rate was of 5%.

conclusionsMalignant obstruction secondary to pancreatic cancer is amenable by ERCP. However, choosing the right stents still varies. SEMS seem to be more efficient on a long term with fewer complications rates and further studies should be performed.

Indexed as

endoscopic retrograde colangio pancreatography (ERCP)Pancreatic cancerplastic stentsself-expendable metal stents (SEMS)

Identifiers

PMID33717505
PMCPMC7948020
OpenAlexW3137567364

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.