Evidence map›Paper›PMID 33717186›Full record

ArticleFrontiers in immunology2021

Treatment of Intestinal Inflammation With Epicutaneous Immunotherapy Requires TGF-β and IL-10 but Not Foxp3

Xin Chen, M Cecilia Berin, Virginia L Gillespie, Hugh A Sampson, David Dunkin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xin ChenDivision of Pediatric Gastroenterology and the Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
M Cecilia BerinDivision of Pediatric Allergy and Immunology, Precision Immunology Institute and Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
Virginia L GillespieCenter for Comparative Medicine and Surgery, The Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
Hugh A SampsonDivision of Pediatric Allergy and Immunology, Precision Immunology Institute and Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
David DunkinDivision of Pediatric Gastroenterology and the Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York City, NY, United States.
Child Health and Development Institute · USDBV Technologies (France) · FRIcahn School of Medicine at Mount Sinai · US

Funding

Epicutaneous Tolerance Induction for the Treatment of ColitisK08DK102978 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DUNKIN, DAVID · 2015 to 2018
$635k
Epicutaneous Tolerance Induction with Flagellin Epitopes for the Treatment of ColitisR03DK117218 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DUNKIN, DAVID · 2018 to 2019
$170k
NIDDK NIH HHS K08 DK102978NIDDK NIH HHS R03 DK117218
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsColitisDiphtheria ToxinForkhead Transcription FactorsImmunotherapy, AdoptiveInflammationInflammatory Bowel DiseasesInterleukin-10IntestinesMiceMice, Inbred C57BLMice, KnockoutOvalbuminT-Lymphocytes, RegulatoryTransforming Growth Factor beta1Diphtheria ToxinForkhead Transcription FactorsFoxp3 protein, mouseIL10 protein, mouseInterleukin-10OvalbuminTgfb1 protein, mouseTransforming Growth Factor beta1colitisepicutaneous immunotherapyIBDimmunotherapyregulatory T cellstolerance

Identifiers

PMID33717186
PMCPMC7952322
OpenAlexW3134320007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.