Evidence map›Paper›PMID 33717184›Full record

ReviewFrontiers in immunology2021

Influence of

Lucas H Armitage, Mark A Wallet, Clayton E Mathews

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. An autoimmunity-associated allele ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. An Autoimmunity-associated allele ofbioRxiv : the preprint server for biology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Advancing Animal Models of Human Type 1 Diabetes.Cold Spring Harbor perspectives in medicine · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. UBASH3A Interacts with PTPN22 to RegulateInternational journal of molecular sciences · 2023
    Article
  18. SNP inInternational journal of molecular sciences · 2023
    Article
  19. Review
  20. eLife · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lucas H ArmitageDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Mark A WalletDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Clayton E MathewsDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
University of Florida · USCentury Therapeutics (United States) · US

Funding

Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9M
Genetic Regulation of Human Beta Cell DestructionUC4DK104194 · NIDDK · UNIVERSITY OF FLORIDA · PI MATHEWS, CLAYTON E · 2014 to 2014
$3.1M
Engineering a Human Microphysiological System for the Characterization of Islet-Immune InteractionsUH3DK122638 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ASHUTOSH, BRUSKO, TODD MICHAEL · 2021 to 2023
$3.0M
Engineering a Human Microphysiological System for the Characterization of Islet-Immune InteractionsUG3DK122638 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ASHUTOSH, BRUSKO, TODD MICHAEL · 2019 to 2020
$2.1M
Interdisciplinary Graduate Program in Type 1 Diabetes and Biomedical EngineeringT32DK108736 · NIDDK · UNIVERSITY OF FLORIDA · PI MARK A. ATKINSON, Benjamin George Keselowsky · 2017 to 2026
$1.9M
NIAID NIH HHS P01 AI042288NIDDK NIH HHS T32 DK108736NIDDK NIH HHS UC4 DK104194NIDDK NIH HHS UG3 DK122638NIDDK NIH HHS UH3 DK122638
6 · The paper itself

Abstract

Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) regulates a panoply of leukocyte signaling pathways. A single nucleotide polymorphism (SNP) in

Indexed as

Adaptive ImmunityAllelesAutoimmunityDiabetes Mellitus, Type 1Genetic Association StudiesGenetic Predisposition to DiseaseHumansImmunity, InnatePolymorphism, Single NucleotideProtein Tyrosine Phosphatase, Non-Receptor Type 22Receptors, Antigen, T-CellT-LymphocytesProtein Tyrosine Phosphatase, Non-Receptor Type 22PTPN22 protein, humanReceptors, Antigen, T-Cellautoimmunitycell signalingleukocytesPTPN22PTPN22 620Arg > Trprs2476601type 1 diabetes

Identifiers

PMID33717184
PMCPMC7946861
OpenAlexW3129988835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.