Evidence map›Paper›PMID 33717144›Full record

ArticleFrontiers in immunology2021

Clinical Profile of Hyper-IgE Syndrome in India.

Biman Saikia, Amit Rawat, Ranjana W Minz, Deepti Suri, Vignesh Pandiarajan, Ankur Jindal, Smrity Sahu, Adil Karim, Mukesh Desai, Prasad D Taur and 16 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Case Report:Frontiers in pediatrics · 2026
    Article
  5. Hyperimmunoglobulin syndromes: A review of HIGM, HIES, and HIDS.Journal of translational autoimmunity · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Dermatologic presentations of hyper IgE syndrome in pediatric patients.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Inherited human ZNF341 deficiency.Current opinion in immunology · 2023
    Review
  16. Long term longitudinal follow-up of an AD-HIES cohort: the impact of early diagnosis and enrollment to IPINet centers on the natural history of Job's syndrome.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 7 institutions in 1 country.

Biman SaikiaDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Amit RawatDepartment of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ranjana W MinzDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Deepti SuriDepartment of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vignesh PandiarajanDepartment of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ankur JindalDepartment of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Smrity SahuDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Adil KarimDepartment of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Mukesh DesaiDepartment of Immunology, BJ Wadia Hospital for Children, Mumbai, India.
Prasad D TaurDepartment of Immunology, BJ Wadia Hospital for Children, Mumbai, India.
Ambreen PandrowalaDepartment of Immunology, BJ Wadia Hospital for Children, Mumbai, India.
Vijaya GowriDepartment of Immunology, BJ Wadia Hospital for Children, Mumbai, India.
Manisha MadkaikarICMR-National Institute of Immunohaematology, Mumbai, India.
Aparna DalviICMR-National Institute of Immunohaematology, Mumbai, India.
Reetika Mallik YadavICMR-National Institute of Immunohaematology, Mumbai, India.
Harsha Prasada LashkariKasturba Medical College, Mangalore, India.
Revathi RajDepartment of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Chennai, India.
Ramya UppuluriDepartment of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Chennai, India.
Venkateswaran V SwaminathanDepartment of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Chennai, India.
Sagar BhattadAster CMI Hospital, Bangalore, India.
Gladys CyrilAster CMI Hospital, Bangalore, India.
Harish KumarAster CMI Hospital, Bangalore, India.
Anuj ShuklaNiruj Rheumatology Clinic, Ahmedabad, India.
Manas KalraSir Ganga Ram Hospital, New Delhi, India.
Geeta GovindarajGovernment Medical College, Kozhikode, Calicut, India.
Surjit SinghDepartment of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INBai Jerbai Wadia Hospital for Children · INApollo Hospitals · INNational Institute of Immunohaematology · INGovernment Medical College · INKasturba Medical College, MangaloreSir Ganga Ram Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultChildChild, PreschoolCohort StudiesEczemaFemaleHumansImmunoglobulin EIndiaInfantJob SyndromeMaleMulticenter Studies as TopicMutationSkinImmunoglobulin ESTAT3 Transcription Factorhyper-IgE syndromeIndiamulti-centric studyrare variantsSTAT3 LOF

Identifiers

PMID33717144
PMCPMC7952512
OpenAlexW3135200627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.