Evidence map›Paper›PMID 33717129›Full record

ArticleFrontiers in immunology2021

Celiac Disease Causes Epithelial Disruption and Regulatory T Cell Recruitment in the Oral Mucosa.

Javier Sanchez-Solares, Luis Sanchez, Carmela Pablo-Torres, Celso Diaz-Fernandez, Poul Sørensen, Domingo Barber, Cristina Gomez-Casado

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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  4. Sequential immunotherapy: towards cures for autoimmunity.Nature reviews. Drug discovery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Javier Sanchez-SolaresInstitute of Applied Molecular Medicine, Hospitals Madrid (HM) Group, San Pablo-CEU University, Madrid, Spain.
Luis SanchezService of Gastroenterology, University Hospital San Agustin (HUSA), Aviles, Spain.
Carmela Pablo-TorresInstitute of Applied Molecular Medicine, Hospitals Madrid (HM) Group, San Pablo-CEU University, Madrid, Spain.
Celso Diaz-FernandezDepartment of Otolaryngology Head and Neck Surgery, University Hospital San Agustin (HUSA), Aviels, Spain.
Poul SørensenAllero Therapeutics BV, Rotterdam, Netherlands.
Domingo BarberInstitute of Applied Molecular Medicine, Hospitals Madrid (HM) Group, San Pablo-CEU University, Madrid, Spain.
Cristina Gomez-CasadoInstitute of Applied Molecular Medicine, Hospitals Madrid (HM) Group, San Pablo-CEU University, Madrid, Spain.
Universidad San Pablo CEU · ESHospital Universitario San Agustín · ESAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is a chronic autoimmune disease characterized by an immune-triggered enteropathy upon gluten intake. The only current treatment available is lifelong Gluten Free Diet (GFD). Several extraintestinal manifestations have been described in CD, some affecting the oral mucosa. Thus, we hypothesized that oral mucosa could potentially be a target for novel biomarkers and an administration route for CD treatment. Six

Indexed as

Chemotaxis, LeukocyteImmunity, MucosalAdultAgedAmphiregulinCase-Control StudiesCeliac DiseaseCytokinesDiet, Gluten-FreeEpithelial CellsFemaleForkhead Transcription FactorsHumansMaleMiddle AgedMouth MucosaAmphiregulinAREG protein, humanCytokinesForkhead Transcription FactorsFOXP3 protein, humanTight Junction Proteinsautoimmune diseaseceliac diseaseimmune mediated disordersimmunotherapyoral mucosaregulatory T cellsremodelingtolerance induction

Identifiers

PMID33717129
PMCPMC7947325
OpenAlexW3133633661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.