Evidence map›Paper›PMID 33717056›Full record

ArticleFrontiers in immunology2020

Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged

Philipp Adams, Gilles Iserentant, Jean-Yves Servais, Linos Vandekerckhove, Guido Vanham, Carole Seguin-Devaux, PhenoCure Study Group

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. An angel or a devil? Current view on the role of CD8Journal of translational medicine · 2024
    Review
  5. Review
  6. Cytolytic CD8Science immunology · 2023
    Article
  7. Review
  8. Role of CXCR5Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Philipp AdamsDepartment of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
Gilles IserentantDepartment of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
Jean-Yves ServaisDepartment of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
Linos VandekerckhoveDepartment of Internal Medicine, Ghent University, Ghent, Belgium.
Guido VanhamDepartments of Biomedical and Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Carole Seguin-DevauxDepartment of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
PhenoCure Study Group
Luxembourg Institute of Health · LUUniversity of Antwerp · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiretroviral therapy (ART) is not curative as HIV-1 persists in long-lived viral reservoirs. Consequently, patients are dependent on life-long drug adherence with possible side effects. To overcome these limitations strategies of a functional cure aim at ART free viral remission. In this study, we sought to identify detailed subsets of anti-viral CD8

Indexed as

PeptidesAdultAgedCD8-Positive T-LymphocytesFemaleGene Expression RegulationHIV-1HIV InfectionsHumansImmunologic MemoryMaleMiddle AgedReceptors, CXCR5CXCR5 protein, humanPeptidesReceptors, CXCR5CXCR5 CD8 T cells + +elite controllersfunctional cureHIV controllersmultifunctional CD8+ T cellsviral suppressive capacity

Identifiers

PMID33717056
PMCPMC7945035
OpenAlexW3131068498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.