Evidence map›Paper›PMID 33717044›Full record

ArticleFrontiers in microbiology2021

New Insights Into the Antibacterial Mechanism of Cryptotanshinone, a Representative Diterpenoid Quinone From

Bo-Chen Chen, Zhi-Shan Ding, Jian-Sheng Dai, Ni-Pi Chen, Xing-Wen Gong, Lie-Feng Ma, Chao-Dong Qian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Cryptotanshinone inhibitsVirulence · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Molecular mechanism ofHorticulture research · 2025
    Article
  7. Inhibitors of Type II NADH Dehydrogenase Enzyme: A Review.Current protein & peptide science · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Bo-Chen ChenCollege of Life Science, Institute of Molecular Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Zhi-Shan DingCollege of Medical Technology, Zhejiang Chinese Medical University, Hangzhou, China.
Jian-Sheng DaiCollege of Life Science, Institute of Molecular Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Ni-Pi ChenCollege of Life Science, Institute of Molecular Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Xing-Wen GongDepartment of Biological Engineering, Zhejiang Gongshang University, Hangzhou, China.
Lie-Feng MaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Chao-Dong QianCollege of Life Science, Institute of Molecular Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CNZhejiang Gongshang University · CNZhejiang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid rise of antibiotic resistance causes an urgent need for new antimicrobial agents with unique and different mechanisms of action. The respiratory chain is one such target involved in the redox balance and energy metabolism. As a natural quinone compound isolated from the root of

Indexed as

cryptotanshinonemenaquinonemetabolome analysisrespiratory chain inhibitortype II NADH:quinone dehydrogenase

Identifiers

PMID33717044
PMCPMC7950322
OpenAlexW3134503002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.