ArticleFrontiers in microbiology2020
Hepatitis E 3ra Genotype Infection in People Living With HIV in Spain.
Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Uncovering the Prevalence and Genetic Characterization of Rabbit-Derived Paslahepevirus Balayani (Hepatitis E Virus) in Hebei Province, China.Food and environmental virology · 2025Article
- Serological and molecular survey of rat hepatitis E virus (Emerging microbes & infections · 2024Article
- Rat hepatitis E virus (Emerging microbes & infections · 2024Article
- Hepatitis E virus in wild and domestic rabbits from Portugal: a combined molecular and longitudinal serological study.Veterinary research communications · 2024Article
- Absence of Hepatitis E Virus (HEV) in Italian Lagomorph Species Sampled between 2019 and 2021.Animals : an open access journal from MDPI · 2023Article
- Monitoring of Hepatitis E Virus in Wild Lagomorphs in Spanish Mediterranean Ecosystems.Transboundary and emerging diseases · 2023Article
- Animal Models for Hepatitis E Virus.Advances in experimental medicine and biology · 2023Article
- Puzzles for Hepatitis E Virus.Advances in experimental medicine and biology · 2023Article
- Molecular epidemiology and genotype-specific disease severity of hepatitis E virus infections in Germany, 2010-2019.Emerging microbes & infections · 2022Article
- Prevalence of Hepatitis E Virus Infection among Laboratory Rabbits in China.Pathogens (Basel, Switzerland) · 2021Article
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of our study was to assess the prevalence and incidence of HEV in people living with HIV (PLWH) in a Spanish national cohort.
methodsRetrospective longitudinal study including PLWH recruited in the cohort of adult HIV-infected patients of the AIDS Research Network in follow-up at 28 Spanish hospitals with available serum samples in 2014 and 2015. All samples were tested for HEV IgG, IgM, and RNA. Samples with detectable HEV viral loads were genotyped. Prevalence and incidence of HEV infection were calculated.
resultsThe study sample comprised 845 PLWH. At baseline, 101 patients were positive for HEV IgG antibodies (11.9%), none had HEV IgM antibodies, and 2 presented detectable HEV RNA (0.23%). Forty-two seroconverted for IgG, supposing a cumulative incidence of 5.7%. One subject was positive for IgM (0.13%), and 2 showed detectable HEV RNA (0.27%). One case was infected by the emergent HEV genotype 3ra.
conclusionOur study identifies one case of HEV 3ra genotype infection, the main host of which is rabbit, showing a potential zoonotic role of this emerging genotype in Spain.
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