SynthesisFrontiers in endocrinology2021
Prevalence of Obesity and Its Impact on Outcome in Patients With COVID-19: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Risk of bias and certainty of evidence on the association between obesity and mortality in patients with SARS-COV-2: An umbrella review of meta-analyses.Clinical nutrition ESPEN · 2023Pooled it
- Obesity augments the disease burden in COVID-19: Updated data from an umbrella review.Clinical obesity · 2022Pooled it
- COVID-19 infection and body weight: A deleterious liaison in a J-curve relationship.Obesity research & clinical practicePooled it
- Feasibility of transthoracic echocardiography in the prone position with a low-cost adaptation: morphological, functional, and hemodynamic analysis.Einstein (Sao Paulo, Brazil) · 2026Article
- Long-term lung function trajectories in Swedish COVID-19 ICU survivors: a two-year follow-up study.European clinical respiratory journal · 2026Article
- Article
- Obesity Parameters as Predictor of Poor Outcomes in Hospitalized Patients with Confirmed Mild-to-Moderate COVID-19.Infectious disease reports · 2024Article
- The impact of obesity in hospitalized patients with COVID-19: a retrospective cohort study.Diabetology & metabolic syndrome · 2024Article
- Predictive biomarkers of mortality in patients with severe COVID-19 hospitalized in intensive care unit.Frontiers in immunology · 2024Article
- [Impact of the COVID pandemic on treatment of bariatric patients in Germany-An analysis of the national StuDoQ/MBE register].Chirurgie (Heidelberg, Germany) · 2023Review
- Impact of COVID-19 on Sedation Requirements during Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome.Journal of clinical medicine · 2023Article
- Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats.Frontiers in endocrinology · 2023Article
- Long-term effects of COVID-19 on the endocrine system - a pilot case-control study.Frontiers in endocrinology · 2023Article
- The Impact of Nonalcoholic Fatty Liver Disease on Severe Community-Acquired Pneumonia Outcomes.Life (Basel, Switzerland) · 2022Article
- Body mass index and clinical outcome of severe COVID-19 patients with acute hypoxic respiratory failure: Unravelling the "obesity paradox" phenomenon.Clinical nutrition ESPEN · 2022Article
- Obesity and Coronavirus Disease 2019.Journal of translational internal medicine · 2022Article
- The changes in cognitive function following bariatric surgery considering the function of gut microbiome.Obesity pillars · 2022Review
- Body-mass index COVID-19 severity: A systematic review of systematic reviews.Journal of family medicine and primary care · 2022Article
- Is obesity paradox valid for critically-ill COVID-19 patients with respiratory failure?Turkish thoracic journal · 2022Article
- Reviving the mutual impact of SARS-COV-2 and obesity on patients: From morbidity to mortality.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Obesity has been reported as a risk factor for adverse outcomes in COVID-19. However, available studies presenting data on obesity prevalence in patients with COVID-19 have conflicting results. The objective of this systematic review and meta-analysis is to evaluate the prevalence of obesity in these patients and to stratify the estimates by illness severity. Methods: We performed a literature search with the use of Medline/PubMed and Google Scholar database from December 1, 2019 to June 27, 2020 and systematically reviewed studies reporting the number of obese patients with real-time reverse transcriptase polymerase chain reaction (rRT-PCR)-confirmed SARS-CoV-2 infection. Results: Nineteen studies were identified. The pooled obesity prevalence rates were 0.32 (95% CI: 0.24-0.41) in hospitalized patients, 0.41 (95% CI: 0.36-0.45) in patients admitted to intensive care unit, 0.43 (95% CI: 0.36-0.51) in patients needing invasive mechanic ventilation (IMV), and 0.33 (95% CI: 0.26-0.41) in those who died. Obesity was associated with a higher risk for hospitalization [Odds ratio (OR): 1.3, 95% CI: 1.00-1.69; I Conclusions: Our data indicate that obese subjects may be at higher risk for serious illness if infected and obesity may play a role in the progression of COVID-19.
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